Literature DB >> 650206

Increased effect of apomorphine on homovanillic acid in rats terminated from chronic haloperidol.

R C Smith, N Narasimhachari, J M Davis.   

Abstract

Rats who were administered apomorphine seven days after termination of chronic treatment with haloperidol had significantly (59%) lower level of brain HVA than saline control rats. This finding is consistent with the behavioral evidence suggesting supersensitivity of post-synaptic dopamine receptors after termination of chronic haloperidol.

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Year:  1978        PMID： 650206     DOI： 10.1007/BF01675355

Source DB:  PubMed          Journal:  J Neural Transm            Impact factor:   3.575


  13 in total

1.  Piribedil and apomorphine: pre- and postsynaptic effects on dopamine synthesis and neuronal activity.

Authors:  J R Walters; B S Bunney; R H Roth
Journal:  Adv Neurol       Date:  1975

2.  Behavioral evidence for supersensitivity after chronic administration of haloperidol, clozapine, and thioridazine.

Authors:  R C Smith; J M Davis
Journal:  Life Sci       Date:  1976-09-01       Impact factor: 5.037

3.  Decrease in homovanillic acid as evidence for dopamine receptor stimulation by apomorphine in the neostriatum of the rat.

Authors:  B E Roos
Journal:  J Pharm Pharmacol       Date:  1969-04       Impact factor: 3.765

4.  Evidence for a receptor-mediated feedback control of striatal tyrosine hydroxylase activity.

Authors:  W Kehr; A Carlsson; M Lindqvist; T Magnusson; C Atack
Journal:  J Pharm Pharmacol       Date:  1972-09       Impact factor: 3.765

5.  Behavioural supersensitivity to apomorphine following chronic treatment with drugs which interfere with the synaptic function of catecholamines.

Authors:  D Tarsy; R J Baldessarini
Journal:  Neuropharmacology       Date:  1974-11       Impact factor: 5.250

6.  Behavioral evidence for dopaminergic supersensitivity after chronic haloperidol.

Authors:  G Gianutsos; R B Drawbaugh; M D Hynes; H Lal
Journal:  Life Sci       Date:  1974-03-01       Impact factor: 5.037

7.  The use of isomeric compounds as internal standards for quantitative mass fragmentography of biological samples. Determination of homovanillic acid in cerebrospinal fluid and plasma.

Authors:  N Narasimhachari
Journal:  Biochem Biophys Res Commun       Date:  1974-01       Impact factor: 3.575

8.  Antischizophrenic drugs: chronic treatment elevates dopamine receptor binding in brain.

Authors:  D R Burt; I Creese; S H Snyder
Journal:  Science       Date:  1977-04-15       Impact factor: 47.728

9.  Behavioral supersensitivity to apomorphine and amphetamine after chronic high dose haloperidol treatment.

Authors:  R C Smith; J M Davis
Journal:  Psychopharmacol Commun       Date:  1975

10.  Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain.

Authors:  J Glowinski; L L Iversen
Journal:  J Neurochem       Date:  1966-08       Impact factor: 5.372
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  1 in total

1.  Dopaminergic supersensitivity: influence of dopamine agonists, cholinergics, anticholinergics, and drugs used for the treatment of tardive dyskinesia.

Authors:  A V Christensen; I M Nielsen
Journal:  Psychopharmacology (Berl)       Date:  1979-04-11       Impact factor: 4.530
  1 in total

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