Literature DB >> 1241453

Behavioral supersensitivity to apomorphine and amphetamine after chronic high dose haloperidol treatment.

R C Smith, J M Davis.   

Abstract

Rats administered chronic haloperidol (5 mg/cc) for 2 months exhibited stereotyped gnawing during chronic haloperidol treatment, and after withdrawal from haloperidol, showed significantly greater stereotyped behavior induced by apomorphine or L-amphetamine compared to saline controls. Chronic administration of benztropine mesylate concomitantly with haloperidol reduced the effects of chronic haloperidol on drug induced stereotyped behavior during the withdrawal period.

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Year:  1975        PMID： 1241453

Source DB:  PubMed          Journal:  Psychopharmacol Commun        ISSN： 0098-616X


  10 in total

1.  Tardive dyskinesia during and following treatment with haloperidol, haloperidol + biperiden, thioridazine, and clozapine.

Authors:  J Gerlach; H Simmelsgaard
Journal:  Psychopharmacology (Berl)       Date:  1978-10-31       Impact factor: 4.530

2.  Continuous, but not intermittent, antipsychotic drug delivery intensifies the pursuit of reward cues.

Authors:  Anne-Marie Bédard; Jérôme Maheux; Daniel Lévesque; Anne-Noël Samaha
Journal:  Neuropsychopharmacology       Date:  2011-02-16       Impact factor: 7.853

3.  Treatment schedule as a determinant of the development of tolerance to haloperidol.

Authors:  R J Carey; J DeVeaugh-Geiss
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

4.  Increased effect of apomorphine on homovanillic acid in rats terminated from chronic haloperidol.

Authors:  R C Smith; N Narasimhachari; J M Davis
Journal:  J Neural Transm       Date:  1978       Impact factor: 3.575

5.  Chronic benztropine and haloperidol administration induce behaviorally equivalent pharmacological hypersensitivities separately but not in combination.

Authors:  R J Carey; J De Veaugh-Geiss
Journal:  Psychopharmacology (Berl)       Date:  1982       Impact factor: 4.530

6.  Prior haloperidol, but not olanzapine, exposure augments the pursuit of reward cues: implications for substance abuse in schizophrenia.

Authors:  Anne-Marie Bédard; Jérôme Maheux; Daniel Lévesque; Anne-Noël Samaha
Journal:  Schizophr Bull       Date:  2012-08-27       Impact factor: 9.306

7.  Alterations in cerebrospinal fluid dopamine metabolites following physostigmine infusion.

Authors:  K L Davis; K F Faull; L E Hollister; J D Barchas; P A Berger
Journal:  Psychopharmacology (Berl)       Date:  1981       Impact factor: 4.530

8.  Differential effects of chronic treatment with chlorpromazine versus cocaine on behavioral responsiveness to nigral GABA receptor stimulation.

Authors:  S E Bachus; K Gale
Journal:  Psychopharmacology (Berl)       Date:  1988       Impact factor: 4.530

9.  Oral dyskinesia in brain-damaged rats withdrawn from a neuroleptic: implication for models of tardive dyskinesia.

Authors:  R B Glassman; H N Glassman
Journal:  Psychopharmacology (Berl)       Date:  1980       Impact factor: 4.530

Review 10.  Recent Discussions on Dopamine Supersensitivity Psychosis: Eight Points to Consider When Diagnosing Treatment-Resistant Schizophrenia.

Authors:  Nobuhisa Kanahara; Hiroshi Kimura; Yasunori Oda; Fumiaki Ito; Masaomi Iyo
Journal:  Curr Neuropharmacol       Date:  2021       Impact factor: 7.708
  10 in total

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