Literature DB >> 6457018

SR-2508: a 2-nitroimidazole amide which should be superior to misonidazole as a radiosensitizer for clinical use.

J M Brown, N Y Yu, D M Brown, W W Lee.   

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Year:  1981        PMID： 6457018     DOI： 10.1016/0360-3016(81)90460-0

Source DB:  PubMed          Journal:  Int J Radiat Oncol Biol Phys        ISSN： 0360-3016            Impact factor:   7.038


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  15 in total

1.  The Radiation Stress Response: Of the People, By the People and For the People.

Authors:  C Norman Coleman
Journal:  Radiat Res       Date:  2017-01-24       Impact factor: 2.841

2.  THNLA-1 as radio/chemosensitiser of EMT-6 tumours in mice.

Authors:  M V Papadopoulou; M Ji; W D Bloomer
Journal:  Br J Cancer Suppl       Date:  1996-07

3.  Structure-pharmacokinetic relationships for misonidazole analogues in mice.

Authors:  P Workman; J M Brown
Journal:  Cancer Chemother Pharmacol       Date:  1981       Impact factor: 3.333

4.  Correlation of partitioning of nitroimidazoles in the n-octanol/saline and liposome systems with pharmacokinetic parameters and quantitative structure-activity relationships (QSAR).

Authors:  G V Betageri; J A Rogers
Journal:  Pharm Res       Date:  1989-05       Impact factor: 4.200

5.  Pharmacokinetic contribution to the improved therapeutic selectivity of a novel bromoethylamino prodrug (RB 6145) of the mixed-function hypoxic cell sensitizer/cytotoxin alpha-(1-aziridinomethyl)-2-nitro-1H-imidazole-1-ethanol (RSU 1069).

Authors:  M Binger; P Workman
Journal:  Cancer Chemother Pharmacol       Date:  1991       Impact factor: 3.333

6.  2-Nitroimidazole potentiation of nitrosourea induced cytotoxicity in subcutaneous implants of rat 9L brain tumor cells.

Authors:  K H Wong; C A Wallen; K T Wheeler
Journal:  J Neurooncol       Date:  1991-08       Impact factor: 4.130

7.  Radiation sensitization and chemopotentiation: RSU 1069, a compound more efficient than misonidazole in vitro and in vivo.

Authors:  G E Adams; I Ahmed; P W Sheldon; I J Stratford
Journal:  Br J Cancer       Date:  1984-05       Impact factor: 7.640

8.  Phase I/pharmacokinetic/biochemical study of the nitroimadazole hypoxic cell sensitiser SR2508 (etanidazole) in combination with cyclophosphamide.

Authors:  P J O'Dwyer; F P LaCreta; J Walczak; T Cox; S Litwin; J P Hoffman; M Zimny; R L Comis
Journal:  Br J Cancer       Date:  1993-10       Impact factor: 7.640

9.  Structure/activity relationships for the enhancement by electron-affinic drugs of the anti-tumour effect of CCNU.

Authors:  P Workman; P R Twentyman
Journal:  Br J Cancer       Date:  1982-08       Impact factor: 7.640

10.  Enhancement of CCNU cytotoxicity by misonidazole: possible therapeutic gain.

Authors:  D G Hirst; J M Brown; J L Hazlehurst
Journal:  Br J Cancer       Date:  1982-07       Impact factor: 7.640
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