Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Impaired metabolism of arachidonate in selenium deficient animals.

Literature DB >> 6403377

Impaired metabolism of arachidonate in selenium deficient animals.

Abstract

Arachidonate-induced respiratory distress in mice was aggravated in a selenium deficient group as compared with a selenium supplemented one. The aggravation in selenium deficient mice may be due to enhanced platelet aggregation and suppressed formation of prostacyclin (PGI2) in the arterial all.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1983 PMID： 6403377 DOI： 10.1007/BF01963149

Source DB: PubMed Journal: Experientia ISSN： 0014-4754

12 in total

1. The production of the arachidonate metabolite HETE in vascular tissue.

Authors: J E Greenwald; J R Bianchine; L K Wong
Journal: Nature Date: 1979-10-18 Impact factor: 49.962

2. Intravenous arachidonate in the mouse: a model for the evaluation of antithrombotic drugs.

Authors: C Kohler; W Wooding; L Ellenbogen
Journal: Thromb Res Date: 1976-07 Impact factor: 3.944

3. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction.

Authors: H Ohkawa; N Ohishi; K Yagi
Journal: Anal Biochem Date: 1979-06 Impact factor: 3.365

4. Role of the arachidonate lipoxygenase pathway in blood platelet aggregation.

Authors: C E Dutilh; E Haddeman; F ten Hoor
Journal: Adv Prostaglandin Thromboxane Res Date: 1980

5. Altered lipoxygenase metabolism and decreased glutathione peroxidase activity in platelets from selenium-deficient rats.

Authors: R W Bryant; J M Bailey
Journal: Biochem Biophys Res Commun Date: 1980-01-15 Impact factor: 3.575

6. Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides.

Authors: R J Gryglewski; S Bunting; S Moncada; R J Flower; J R Vane
Journal: Prostaglandins Date: 1976-11

2. Selenium enhances glutathione peroxidase activity and prostacyclin release in cultured human endothelial cells. Concurrent effects on mRNA levels.

Authors: M M Ricetti; G C Guidi; G Bellisola; R Marrocchella; A Rigo; G Perona
Journal: Biol Trace Elem Res Date: 1994 Oct-Nov Impact factor: 3.738

2 in total

Impaired metabolism of arachidonate in selenium deficient animals.

1. The production of the arachidonate metabolite HETE in vascular tissue.

2. Intravenous arachidonate in the mouse: a model for the evaluation of antithrombotic drugs.

3. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction.

4. Role of the arachidonate lipoxygenase pathway in blood platelet aggregation.

5. Altered lipoxygenase metabolism and decreased glutathione peroxidase activity in platelets from selenium-deficient rats.

6. Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides.

7. Selenium: biochemical role as a component of glutathione peroxidase.

8. Coronary tone modulation: formation and actions of prostaglandins, endoperoxides, and thromboxanes.

9. Arachidonic acid causes sudden death in rabbits.

10. Thromboxanes: a new group of biologically active compounds derived from prostaglandin endoperoxides.

Review 1. Physiological and nutritional importance of selenium.

2. Selenium enhances glutathione peroxidase activity and prostacyclin release in cultured human endothelial cells. Concurrent effects on mRNA levels.