Literature DB >> 638033

Hepatic blood flow studies in the rat before and after portacaval transposition.

C J Ryan, J Guest, S Ryan, A M Harper, L H Blumgart.   

Abstract

Portacaval transposition diverts portal blood from the liver and allows systemic venous blood from the caudal inferior vena cava to perfuse the portal bed. Measurement of hepatic tissue blood flow before and after portacaval transposition and its relationship to the liver atrophy seen after portacaval transposition is important. Sequential measurements of hepatic tissue blood flow carried out before and after portacaval transposition have been made using the clearance of the inert radioactive gas 85Krypton after injection into the portal bed. These measurements reveal that hepatic tissue blood flow is not diminished following the operation. The relative liver atrophy seen after portacaval transposition is therefore consequent on portal venous diversion but not on diminished hepatic perfusion.

Entities:  

Mesh:

Year:  1978        PMID: 638033      PMCID: PMC2041314     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN: 0007-1021


  10 in total

Review 1.  REGENERATION OF MAMMALIAN LIVER.

Authors:  N L BUCHER
Journal:  Int Rev Cytol       Date:  1963

2.  Studies on hepatic blood flow and the rate of bromsulphalein clearance in dogs with portacaval transposition.

Authors:  T E STARZL; W A SCANLON; W C SHOEMAKER; F H THORNTON; R M WENDEL; L SCHLACHTER
Journal:  Surgery       Date:  1962-10       Impact factor: 3.982

3.  The relation between hepatic flow and function in normal dogs and dogs with cirrhosis after portacaval shunt or transposition.

Authors:  F W HEER; D E SILVIUS; H A HARPER
Journal:  Surg Forum       Date:  1960

4.  The solubility of 85Krypton in the regenerating liver of the rat.

Authors:  R T Mathie; D P Leiberman; A M Harper; L H Blumgart
Journal:  Br J Exp Pathol       Date:  1977-06

5.  Portacaval transposition in the rat: a new technique and its effects on liver and body weight.

Authors:  C J Ryan; I S Benjamin; L H Blumgart
Journal:  Br J Surg       Date:  1974-03       Impact factor: 6.939

6.  Portacaval transposition and subsequent partial hepatectomy in the rat: effects on liver atrophy, hypertrophy and regenerative hyperplasia.

Authors:  J Guest; C J Ryan; I S Benjamin; L H Blumgart
Journal:  Br J Exp Pathol       Date:  1977-04

7.  Measurement of liver blood flow in the rat using an 85Krypton clearance technique.

Authors:  G C Rice; C J Ryan; D P Leiberman; R T Mathie; E McGhee; A M Harper; L H Blumgart
Journal:  Br J Exp Pathol       Date:  1977-06

8.  Liver tissue blood flow measured by 85Kr clearance in the anaesthetized rat before and after partial hepatectomy.

Authors:  G C Rice; D P Leiberman; R T Mathie; C J Ryan; A M Harper; L H Blumgart
Journal:  Br J Exp Pathol       Date:  1977-06

9.  Effects of insulin, glucagon, and insuling/glucagon infusions on liver morphology and cell division after complete portacaval shunt in dogs.

Authors:  T E Starzl; K Watanabe; K A Porter; C W Putnam
Journal:  Lancet       Date:  1976-04-17       Impact factor: 79.321

10.  Portal hepatotrophic factors, diabetes mellitus and acute liver atrophy, hypertrophy and regeneration.

Authors:  T E Starzl; K A Porter; N Kashiwagi
Journal:  Surg Gynecol Obstet       Date:  1975-12
  10 in total
  5 in total

1.  High perfusion pressure damages the sieving ability of sinusoidal endothelium in rat livers.

Authors:  R Fraser; L M Bowler; W A Day; B Dobbs; H D Johnson; D Lee
Journal:  Br J Exp Pathol       Date:  1980-04

2.  Liver blood flow measurements in the portacavally transposed rat before and after partial hepatectomy.

Authors:  C J Ryan; J Guest; A M Harper; L H Blumgart
Journal:  Br J Exp Pathol       Date:  1978-04

3.  Differentiation between the effects of unprocessed portal blood and reduced liver function on brain indole amine metabolism in the portacaval shunted rat.

Authors:  B Alexander; M Aslam; A Nobin; I S Benjamin
Journal:  Metab Brain Dis       Date:  1998-06       Impact factor: 3.584

4.  Changes in the nuclei of astrocytes following portacaval shunting and portacaval transposition in the rat.

Authors:  D Doyle; C J Ryan; I S Benjamin; L H Blumgart
Journal:  Br J Exp Pathol       Date:  1978-10

5.  Activated charcoal haemoperfusion via an extracorporeal circuit in the unrestrained and unanaesthetized rat.

Authors:  C J Ryan; J M Courtney; C B Wood; R G Hood; L H Blumgart
Journal:  Br J Exp Pathol       Date:  1979-08
  5 in total

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