Literature DB >> 326287

Measurement of liver blood flow in the rat using an 85Krypton clearance technique.

G C Rice, C J Ryan, D P Leiberman, R T Mathie, E McGhee, A M Harper, L H Blumgart.   

Abstract

A method for the measurement of liver blood flow (LBF) in rats has been developed by recording the clearance of 85Kr from the liver after injection of a solution of the gas into the portal vein. This technique provides a measure of tissue perfusion at a cellular level. The animal preparation was maintained in a stable haemodynamic and respiratory state for up to 4-3 h by careful fluid and anaesthetic control. Stability of the model was reflected by relative constancy of the LBF measured throughout the experiment in all of the animals studied. The mean LBF determined in six rats was 2-41+/-(s.d.) 0-50 ml/g/min.

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Year:  1977        PMID： 326287      PMCID： PMC2041145     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN： 0007-1021


  19 in total

1.  The use of indocyanine green in the measurement of hepatic blood flow and as a test of hepatic function.

Authors:  J CAESAR; S SHALDON; L CHIANDUSSI; L GUEVARA; S SHERLOCK
Journal:  Clin Sci       Date:  1961-08       Impact factor: 6.124

2.  Estimation of hepatic blood flow in man and in dogs by I 131-labeled rose bengal; simultaneous comparison with sulfobromophthalein sodium.

Authors:  B COMBES
Journal:  J Lab Clin Med       Date:  1960-10

3.  Measurement of hepatic blood flow by bromsulphalein and by the electromagnetic flowmeter.

Authors:  T DRAPANAS; D N KLUGE; W G SCHENK
Journal:  Surgery       Date:  1960-12       Impact factor: 3.982

4.  The measurement of local cortical blood flow in the brain by the analysis of the clearance curve of krypton-85.

Authors:  H I GLASS; A M HARPER; M M GLOVER
Journal:  Phys Med Biol       Date:  1961-07       Impact factor: 3.609

5.  Measurement of hepatic blood flow by indicator dilution techniques.

Authors:  S REICHMAN; W D DAVIS; J P STORAASLI; R GORLIN
Journal:  J Clin Invest       Date:  1958-12       Impact factor: 14.808

6.  Fate of radioactive kryton (Kr85) introduced intravenously in man.

Authors:  C A CHIDSEY; H W FRITTS; A HARDEWIG; D W RICHARDS; A COURNAND
Journal:  J Appl Physiol       Date:  1959-01       Impact factor: 3.531

7.  The measurement of liver blood flow in partially hepatectomized rats.

Authors:  B BENACERRAF; D BILBEY; G BIOZZI; B N HALPERN; C STIFFEL
Journal:  J Physiol       Date:  1957-04-30       Impact factor: 5.182

8.  The solubility of 85Krypton in the regenerating liver of the rat.

Authors:  R T Mathie; D P Leiberman; A M Harper; L H Blumgart
Journal:  Br J Exp Pathol       Date:  1977-06

9.  Reference sample method for cardiac output and regional blood flow determinations in the rat.

Authors:  A B Malik; J E Kaplan; T M Saba
Journal:  J Appl Physiol       Date:  1976-03       Impact factor: 3.531

10.  Liver blood flow measurement the interpretation of xenon133 clearance curves.

Authors:  R J Mackenzie; D P Leiberman; R T Mathie; G C Rice; A M Harper; L H Blumgart
Journal:  Acta Chir Scand       Date:  1976
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  10 in total

1.  Changes in liver blood flow after hepatectomy in conscious dogs.

Authors:  T Sato; A Yasui; S Kondo; M Kato; N Kameoka; Y Nimura
Journal:  Surg Today       Date:  1996       Impact factor: 2.549

2.  Measurement of hepatic blood flow in the rat using fractional clearance of indocyanine green and colloidal radiogold.

Authors:  D Lebrec; L Blanchet; S Lacroix
Journal:  Pflugers Arch       Date:  1981-10       Impact factor: 3.657

3.  Hepatic blood flow studies in the rat before and after portacaval transposition.

Authors:  C J Ryan; J Guest; S Ryan; A M Harper; L H Blumgart
Journal:  Br J Exp Pathol       Date:  1978-02

4.  Radioxenon washout from the dog liver: a comparison of portal venous and hepatic arterial injections.

Authors:  A M Peters; T G Richards
Journal:  Pflugers Arch       Date:  1980-03       Impact factor: 3.657

5.  Liver blood flow measurements in the portacavally transposed rat before and after partial hepatectomy.

Authors:  C J Ryan; J Guest; A M Harper; L H Blumgart
Journal:  Br J Exp Pathol       Date:  1978-04

6.  Liver tissue blood flow measured by 85Kr clearance in the anaesthetized rat before and after partial hepatectomy.

Authors:  G C Rice; D P Leiberman; R T Mathie; C J Ryan; A M Harper; L H Blumgart
Journal:  Br J Exp Pathol       Date:  1977-06

7.  Activated charcoal haemoperfusion via an extracorporeal circuit in the unrestrained and unanaesthetized rat.

Authors:  C J Ryan; J M Courtney; C B Wood; R G Hood; L H Blumgart
Journal:  Br J Exp Pathol       Date:  1979-08

8.  Pharmacokinetics of 5-fluorouracil infusions in the rat: comparison with man and other species.

Authors:  J M Collins
Journal:  Cancer Chemother Pharmacol       Date:  1985       Impact factor: 3.333

9.  Hepatic arterial spin labelling MRI: an initial evaluation in mice.

Authors:  R Ramasawmy; A E Campbell-Washburn; J A Wells; S P Johnson; R B Pedley; S Walker-Samuel; M F Lythgoe
Journal:  NMR Biomed       Date:  2014-12-17       Impact factor: 4.044

10.  Liver perfusion MRI in a rodent model of cirrhosis: Agreement with bulk-flow phase-contrast MRI and noninvasive evaluation of inflammation in chronic liver disease using flow-sensitive alternating inversion recovery arterial spin labelling and tissue T1.

Authors:  Manil Dinesh Chouhan; Rajiv Ramasawmy; Alan Bainbridge; Adrienne Campbell-Washburn; Steve Halligan; Nathan Davies; Simon Walker-Samuel; Mark F Lythgoe; Rajeshwar Prosad Mookerjee; Stuart Andrew Taylor
Journal:  NMR Biomed       Date:  2020-10-07       Impact factor: 4.478
  10 in total

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