Literature DB >> 638026

Biosynthesis and release of prostaglandins by mast cells.

G Tolone, L Bonasera, C Tolone.   

Abstract

Rat mast cells, isolated from peritoneal fluids, were found to release substantial amounts of immunoreactive E-type prostaglandin when stimulated in vitro by foetal calf serum or incubated in the presence of arachidonic acid. Extracellular accumulation of iPGE reflected synthesis, rather than release of preformed material, since it was abolished by indomethacin, a potent and relatively specific inhibitor of prostaglandin synthetase. Hydrocortisone and Compound 48/80, in such experimental conditions, did not affect PGE release.

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Year:  1978        PMID： 638026      PMCID： PMC2041318     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN： 0007-1021


  22 in total

1.  Corticosteroids inhibit prostaglandin production by rheumatiod synovia.

Authors:  F Kantrowitz; D R Robinson; M B McGuire; L Levine
Journal:  Nature       Date:  1975-12-25       Impact factor: 49.962

2.  Stimulation of prostaglandin E synthesis in cultured human umbilical vein smooth muscle cells.

Authors:  R W Alexander; M A Gimbrone
Journal:  Proc Natl Acad Sci U S A       Date:  1976-05       Impact factor: 11.205

3.  Inhibition of release of prostaglandins as an explanation of some of the actions of anti-inflammatory corticosteroids.

Authors:  G P Lewis; P J Piper
Journal:  Nature       Date:  1975-03-27       Impact factor: 49.962

4.  Prostaglandin production by human polymorphnuclear leucocytes during phagocytosis in vitro.

Authors:  G Tolone; L Bonasera; M Brai; C Tolone
Journal:  Experientia       Date:  1977-07-15

5.  Control of lymphokine secretion by prostaglandins.

Authors:  D Gordon; M A Bray; J Morley
Journal:  Nature       Date:  1976-07-29       Impact factor: 49.962

6.  Macrophages synthesis and release prostaglandins in response to inflammatory stimuli.

Authors:  J L Humes; R J Bonney; L Pelus; M E Dahlgren; S J Sadowski; F A Kuehl; P Davies
Journal:  Nature       Date:  1977-09-08       Impact factor: 49.962

7.  Dissociation of the immunologic release of histamine and slow reacting substance of anaphylaxis from human lung using cytochalasins A and B-1.

Authors:  R P Orange
Journal:  J Immunol       Date:  1975-01       Impact factor: 5.422

8.  Modulation of cyclic AMP in purified rat mast cells. I. Responses to pharmacologic, metabolic, and physical stimuli.

Authors:  T J Sullivan; K L Parker; W Stenson; C W Parker
Journal:  J Immunol       Date:  1975-05       Impact factor: 5.422

9.  Inhibition of arachidonic acid release from cells as the biochemical action of anti-inflammatory corticosteroids.

Authors:  S L Hong; L Levine
Journal:  Proc Natl Acad Sci U S A       Date:  1976-05       Impact factor: 11.205

10.  Release of histamine and formation of prostaglandins in human lung tissue and rat mast cells.

Authors:  K Strandberg; A A Mathé; S S Yen
Journal:  Int Arch Allergy Appl Immunol       Date:  1977
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  4 in total

1.  Influence of hydrocortisone on the modulation of the inflammatory response.

Authors:  G Tolone; L Bonasera; C Tolone
Journal:  Br J Exp Pathol       Date:  1978-08

2.  Hydrocortisone increases the responsiveness of mast cells to beta-adrenergic agonists by an action distal to the beta-adrenoreceptors.

Authors:  G Tolone; L Bonasera; R Sajeva
Journal:  Br J Exp Pathol       Date:  1979-06

3.  Fatal antral ulcer in conventionally fed W/Wv mutant mice given indomethacin by injection.

Authors:  M Yokoyama; M Tomoi; T Taguchi; T Nakano; H Asai; T Ono; Y Kitamura
Journal:  Am J Pathol       Date:  1985-06       Impact factor: 4.307

Review 4.  Regulation of allergic responses by prostaglandins: a review.

Authors:  J Morley; J L Beets; M A Bray; W Paul
Journal:  J R Soc Med       Date:  1980-06       Impact factor: 18.000
  4 in total

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