| Literature DB >> 6370829 |
Abstract
The information published on human oncogenes up to the fall of 1983 is reviewed. Retroviral oncogenes, proto-oncogenes, and cellular transforming genes are compared. Transforming genes derived from the ras gene family are described in detail. The different mechanisms of activation of proto-oncogenes are summarized. Finally, the concerted or sequential action of cellular transforming genes in the multi-step process of carcinogenesis is discussed.Entities:
Mesh:
Substances:
Year: 1984 PMID: 6370829 DOI: 10.1007/bf00286587
Source DB: PubMed Journal: Hum Genet ISSN: 0340-6717 Impact factor: 4.132