| Literature DB >> 6350893 |
Abstract
Fifty-five-kilobase long artificial chromosomes containing cloned genes, replicators, centromeres and telomeres have been constructed in yeast. These molecules have many of the properties of natural yeast chromosomes. Centromere function is impaired on short (less than 20 kilobases) artificial chromosomes.Entities:
Mesh:
Year: 1983 PMID: 6350893 DOI: 10.1038/305189a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962