Literature DB >> 634355

Brain histamine receptors as targets for antidepressant drugs.

P D Kanof, P Greengard.   

Abstract

A large number of structurally diverse drugs with clinical antidepressant properties share the ability to act as potent inhibitors of histamine-sensitive adenylate cyclase in cell-free preparations from mammalian brain. This common biochemical action may represent part of the molecular basis for the antidepressant properties of these compounds.

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Year:  1978        PMID： 634355     DOI： 10.1038/272329a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  47 in total

Review 1.  Histamine receptors in the central nervous system.

Authors:  H Timmerman
Journal:  Pharm Weekbl Sci       Date:  1989-10-20

2.  Analysis of competitive antagonism when this property occurs as part of a pharmacological resultant.

Authors:  J W Black; V P Gerskowitch; P Leff; N P Shankley
Journal:  Br J Pharmacol       Date:  1986-11       Impact factor: 8.739

3.  Effects of antidepressant agents on the synthesis of brain monoamines.

Authors:  A Carlsson; M Lindqvist
Journal:  J Neural Transm       Date:  1978       Impact factor: 3.575

4.  Differential effects of ovarian steroid hormones on beta-adrenoceptor downregulation caused by the antidepressants imipramine and rolipram.

Authors:  J E Schultz; H Rösch
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1991-10       Impact factor: 3.000

Review 5.  Neurobiology of brain-gut interactions. Implications for ulcer disease.

Authors:  D E Hernandez
Journal:  Dig Dis Sci       Date:  1989-12       Impact factor: 3.199

6.  Acceleration of rat brain beta-adrenoceptor subsensitivity following the coadministration of histamine receptor antagonists with imipramine.

Authors:  A A Alhaider; A A Mustafa
Journal:  Agents Actions       Date:  1989-11

7.  The localization of [3H]-desipramine in central nerve terminals studied with electron microscope autoradiography and subcellular fractionation.

Authors:  Z Yavin; A Biegon; R Hofstein; D Samuel
Journal:  Experientia       Date:  1979-09-15

8.  Differences in presynaptic alpha-blockade, noradrenaline uptake inhibition, and potential antidepressant activity between (+)- and (-)mianserin.

Authors:  H Schoemaker; H H Berendsen; H J Stevens; V J Nickolson
Journal:  Psychopharmacology (Berl)       Date:  1981       Impact factor: 4.530

Review 9.  Mianserin: a review of its pharmacological properties and therapeutic efficacy in depressive illness.

Authors:  R N Brogden; R C Heel; T M Speight; G S Avery
Journal:  Drugs       Date:  1978-10       Impact factor: 9.546

10.  Paraganglionic cell response to chronic imipramine and handling stress: an ultrastructural study.

Authors:  J C Folan; O Johansson; C Heym
Journal:  J Neural Transm Gen Sect       Date:  1990
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