Literature DB >> 6337651

X-ray diffraction study of the zinc(II) binding sites in yeast phenylalanine transfer RNA. Preferential binding of zinc to guanines in purine-purine sequences.

J R Rubin, J Wang, M Sundaralingam.   

Abstract

An X-ray diffraction study of a zinc(II) complex of tRNAPhe from yeast reveals the present of five zinc-binding sites on the tRNA molecule. Two of the cooperatively bound Mg2+ in the native tRNA structure are replaced by Zn2+. The remaining sites involve direct coordination of zinc to the N7 position of tRNA guanine bases, G15, G43 and HG45. Thus, zinc displays a high specificity for binding to guanine bases in purine-purine sequences.

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Year:  1983        PMID: 6337651     DOI: 10.1016/0304-4165(83)90030-2

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  9 in total

1.  The crystal structure of yeast phenylalanine tRNA at 1.93 A resolution: a classic structure revisited.

Authors:  H Shi; P B Moore
Journal:  RNA       Date:  2000-08       Impact factor: 4.942

2.  Thiophilic metal ion rescue of phosphorothioate interference within the Tetrahymena ribozyme P4-P6 domain.

Authors:  S Basu; S A Strobel
Journal:  RNA       Date:  1999-11       Impact factor: 4.942

3.  Selection of an RNA domain that binds Zn2+.

Authors:  J Ciesiolka; J Gorski; M Yarus
Journal:  RNA       Date:  1995-07       Impact factor: 4.942

4.  Divalent metal ion binding to a conserved wobble pair defining the upstream site of cleavage of group I self-splicing introns.

Authors:  F H Allain; G Varani
Journal:  Nucleic Acids Res       Date:  1995-02-11       Impact factor: 16.971

5.  Site-specific cleavage by metal ion cofactors and inhibitors of M1 RNA, the catalytic subunit of RNase P from Escherichia coli.

Authors:  S Kazakov; S Altman
Journal:  Proc Natl Acad Sci U S A       Date:  1991-10-15       Impact factor: 11.205

6.  In vitro selection and characterization of a highly efficient Zn(II)-dependent RNA-cleaving deoxyribozyme.

Authors:  J Li; W Zheng; A H Kwon; Y Lu
Journal:  Nucleic Acids Res       Date:  2000-01-15       Impact factor: 16.971

7.  Biochemical and Biophysical Understanding of Metal Ion Selectivity of DNAzymes.

Authors:  Kevin Hwang; Parisa Hosseinzadeh; Yi Lu
Journal:  Inorganica Chim Acta       Date:  2016-04-23       Impact factor: 2.545

8.  Similar binding of the carcinostatic drugs cis-[Pt(NH3)2Cl2] and [Ru(NH3)5Cl] Cl2 to tRNAphe and a comparison with the binding of the inactive trans-[Pt(NH3)2Cl2] complex - reluctance in binding to Watson-Crick base pairs within double helix.

Authors:  J R Rubin; M Sabat; M Sundaralingam
Journal:  Nucleic Acids Res       Date:  1983-09-24       Impact factor: 16.971

9.  Studies on Escherichia coli RNase P RNA with Zn2+ as the catalytic cofactor.

Authors:  Simona Cuzic; Roland K Hartmann
Journal:  Nucleic Acids Res       Date:  2005-05-02       Impact factor: 16.971

  9 in total

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