Literature DB >> 6332115

In vivo measurement of regional cerebral haematocrit using positron emission tomography.

A A Lammertsma, D J Brooks, R P Beaney, D R Turton, M J Kensett, J D Heather, J Marshall, T Jones.   

Abstract

A method is described for measuring the regional cerebral-to-large vessel haematocrit ratio using inhalation of carbon-11-labelled carbon monoxide and the intravenous injection of carbon-11-labelled methyl-albumin in combination with positron emission tomography. The mean value in a series of nine subjects was 0.69. This is approximately 20% lower than the value of 0.85 previously reported. It is concluded that previous measurements of regional cerebral blood volume using a haematocrit ratio of 0.85 will have underestimated the value of regional cerebral blood volume by 20%.

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Year:  1984        PMID： 6332115     DOI： 10.1038/jcbfm.1984.47

Source DB:  PubMed          Journal:  J Cereb Blood Flow Metab        ISSN： 0271-678X            Impact factor:   6.200


  16 in total

1.  Monitoring of cerebral perfusion pressure during intracranial hypertension: a sufficient parameter of adequate cerebral perfusion and oxygenation?

Authors:  Christof Thees; Kai-Michael Scheufler; Joachim Nadstawek; Josef Zentner; Ariane Lehnert; Andreas Hoeft
Journal:  Intensive Care Med       Date:  2003-01-23       Impact factor: 17.440

2.  Quantitative cerebral blood flow in dynamic susceptibility contrast MRI using total cerebral flow from phase contrast magnetic resonance angiography.

Authors:  David Bonekamp; Mahaveer Degaonkar; Peter B Barker
Journal:  Magn Reson Med       Date:  2011-02-01       Impact factor: 4.668

3.  The new FDG brain revolution: the neurovascular unit and the default network.

Authors:  Stelvio Sestini; Antonio Castagnoli; Luigi Mansi
Journal:  Eur J Nucl Med Mol Imaging       Date:  2010-05       Impact factor: 9.236

Review 4.  Absolute quantification of perfusion using dynamic susceptibility contrast MRI: pitfalls and possibilities.

Authors:  Linda Knutsson; Freddy Ståhlberg; Ronnie Wirestam
Journal:  MAGMA       Date:  2009-12-04       Impact factor: 2.310

5.  Haemodilution and oxygen transport capacity.

Authors:  A Haass; F Jung
Journal:  J Neurol       Date:  1990-04       Impact factor: 4.849

Review 6.  Positron emission tomography and in vivo measurements of tumour perfusion and oxygen utilisation.

Authors:  A A Lammertsma
Journal:  Cancer Metastasis Rev       Date:  1987       Impact factor: 9.264

7.  Dynamic model for the tissue concentration and oxygen saturation of hemoglobin in relation to blood volume, flow velocity, and oxygen consumption: Implications for functional neuroimaging and coherent hemodynamics spectroscopy (CHS).

Authors:  Sergio Fantini
Journal:  Neuroimage       Date:  2013-04-10       Impact factor: 6.556

8.  Cerebral haemodynamics in preterm infants after exposure to dexamethasone.

Authors:  A Pellicer; F Gayá; T A Stiris; J Quero; F Cabañas
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  1998-09       Impact factor: 5.747

9.  Intravascular contrast agent T2* relaxivity in brain tissue.

Authors:  Vishal Patil; Jens H Jensen; Glyn Johnson
Journal:  NMR Biomed       Date:  2012-12-06       Impact factor: 4.044

10.  Cerebral haemodynamic changes after extracranial-intracranial bypass surgery.

Authors:  J M Gibbs; R J Wise; D J Thomas; A O Mansfield; R W Russell
Journal:  J Neurol Neurosurg Psychiatry       Date:  1987-02       Impact factor: 10.154
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