Literature DB >> 3327631

Positron emission tomography and in vivo measurements of tumour perfusion and oxygen utilisation.

A A Lammertsma1.   

Abstract

The advent of positron emission tomography has provided the clinical investigator with a tool for performing noninvasive (patho)-physiological measurements in humans. The method has been used extensively in the study of cerebral and cardiovascular disease. Oncological applications have been described by a more limited number of centres and have mainly concentrated on cerebral tumours. The first part of this review discusses principles of positron emission tomography and requirements for performing quantitative studies. The second part describes results of one of the most important quantitative techniques: the measurement of tumour blood flow and oxygen metabolism.

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Year:  1987        PMID： 3327631     DOI： 10.1007/bf00047466

Source DB:  PubMed          Journal:  Cancer Metastasis Rev        ISSN： 0167-7659            Impact factor:   9.264


  34 in total

1.  Application of annihilation coincidence detection to transaxial reconstruction tomography.

Authors:  M E Phelps; E J Hoffman; N A Mullani; M M Ter-Pogossian
Journal:  J Nucl Med       Date:  1975-03       Impact factor: 10.057

2.  Design and performance characteristics of a whole-body positron transaxial tomograph.

Authors:  E J Hoffmann; M E Phelps; N A Mullani; C S Higgins; M M Ter-Pogossian
Journal:  J Nucl Med       Date:  1976-06       Impact factor: 10.057

3.  Correction for the presence of intravascular oxygen-15 in the steady-state technique for measuring regional oxygen extraction ratio in the brain: 2. Results in normal subjects and brain tumour and stroke patients.

Authors:  A A Lammertsma; R J Wise; J D Heather; J M Gibbs; K L Leenders; R S Frackowiak; C G Rhodes; T Jones
Journal:  J Cereb Blood Flow Metab       Date:  1983-12       Impact factor: 6.200

4.  Regional cerebral oxygen supply and utilization in dementia. A clinical and physiological study with oxygen-15 and positron tomography.

Authors:  R S Frackowiak; C Pozzilli; N J Legg; G H Du Boulay; J Marshall; G L Lenzi; T Jones
Journal:  Brain       Date:  1981-12       Impact factor: 13.501

5.  Error analysis for the determination of cerebral blood flow with the continuous inhalation of 15O-labeled carbon dioxide and positron emission tomography.

Authors:  S C Jones; J H Greenberg; M Reivich
Journal:  J Comput Assist Tomogr       Date:  1982-02       Impact factor: 1.826

6.  Blood flow and oxygen utilisation in the contralateral cerebral cortex of patients with untreated intracranial tumours as studied by positron emission tomography, with observations on the effect of decompressive surgery.

Authors:  R P Beaney; D J Brooks; K L Leenders; D G Thomas; T Jones; K E Halnan
Journal:  J Neurol Neurosurg Psychiatry       Date:  1985-04       Impact factor: 10.154

7.  In vivo disturbance of the oxidative metabolism of glucose in human cerebral gliomas.

Authors:  C G Rhodes; R J Wise; J M Gibbs; R S Frackowiak; J Hatazawa; A J Palmer; D G Thomas; T Jones
Journal:  Ann Neurol       Date:  1983-12       Impact factor: 10.422

8.  ECAT: a new computerized tomographic imaging system for positron-emitting radiopharmaceuticals.

Authors:  M E Phelps; E J Hoffman; S C Huang; D E Kuhl
Journal:  J Nucl Med       Date:  1978-06       Impact factor: 10.057

9.  Serial observations on the pathophysiology of acute stroke. The transition from ischaemia to infarction as reflected in regional oxygen extraction.

Authors:  R J Wise; S Bernardi; R S Frackowiak; N J Legg; T Jones
Journal:  Brain       Date:  1983-03       Impact factor: 13.501

10.  The requirement for constant arterial radioactivity in the C15O2 steady-state blood-flow model.

Authors:  E Meyer; Y L Yamamoto
Journal:  J Nucl Med       Date:  1984-04       Impact factor: 10.057
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  1 in total

1.  Geographical mapping of metabolites in biological tissue with quantitative bioluminescence and single photon imaging.

Authors:  W Mueller-Klieser; S Walenta
Journal:  Histochem J       Date:  1993-06
  1 in total

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