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Literature DB >> 6332077

Interleukin 1 production by peripheral blood mononuclear cells from leprosy patients.

S Watson, W Bullock, K Nelson, V Schauf, R Gelber, R Jacobson.

Abstract

Quantitation of interleukin 1 production by adherent mononuclear cells from peripheral blood was performed in patients with tuberculoid and lepromatous forms of leprosy. Cells from patients with tuberculoid leprosy either secreted interleukin 1 spontaneously or produced amounts within the normal range in response to lipopolysaccharide stimulation. Conversely, stimulated cells from lepromatous patients failed to produce interleukin 1 in 5 of 13 (38.5%) cases.

Entities: Disease Gene Species

Mesh：

Substances：
Interleukin-1

Year: 1984 PMID： 6332077 PMCID： PMC263369 DOI： 10.1128/iai.45.3.787-789.1984

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

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