Literature DB >> 6327335

Direct action of pertussis toxin in isolated hamster fat cells.

M A Martínez-Olmedo, J A García-Sáinz.   

Abstract

Incubation of pieces of adipose tissue in the presence of pertussis toxin (10-100 micrograms/ml) resulted in blockade in the isolated fat cells of the action of agents that inhibit adenylate cyclase through receptor-mediated GTP-dependent processes (alpha 2-adrenergic amines, prostaglandins, Ri-adenosine, nicotinic acid) and enhancement of the action of isoproterenol. There was a lag period of approximately 2 h for the action of the toxin.

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Year:  1984        PMID: 6327335     DOI: 10.1016/0014-2999(84)90441-2

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN: 0014-2999            Impact factor:   4.432


  5 in total

1.  Islet-activating protein (pertussis toxin) diminishes alpha 2-adrenoceptor mediated effects on noradrenaline release.

Authors:  C Allgaier; T J Feuerstein; R Jackisch; G Hertting
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1985-11       Impact factor: 3.000

2.  Rat fat-cells have three types of adenosine receptors (Ra, Ri and P). Differential effects of pertussis toxin.

Authors:  J A García-Sáinz; M L Torner
Journal:  Biochem J       Date:  1985-12-01       Impact factor: 3.857

3.  Participation of protein kinase C and regulatory G proteins in modulation of the evoked noradrenaline release in brain.

Authors:  G Hertting; C Allgaier
Journal:  Cell Mol Neurobiol       Date:  1988-03       Impact factor: 5.046

4.  Pertussis vaccine reduces agonist binding to the rat heart muscarinic receptor and its guanine nucleotide modulation.

Authors:  J S Aguilar; M I Fonseca; E De Robertis
Journal:  Neurochem Res       Date:  1986-05       Impact factor: 3.996

5.  Per- and Polyfluoroalkyl Substances Differentially Inhibit Placental Trophoblast Migration and Invasion In Vitro.

Authors:  John T Szilagyi; Anastasia N Freedman; Stewart L Kepper; Arjun M Keshava; Jackie T Bangma; Rebecca C Fry
Journal:  Toxicol Sci       Date:  2020-06-01       Impact factor: 4.849

  5 in total

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