Literature DB >> 6326055

The human myoglobin gene: a third dispersed globin locus in the human genome.

A J Jeffreys, V Wilson, A Blanchetot, P Weller, A Geurts van Kessel, N Spurr, E Solomon, P Goodfellow.   

Abstract

Human myoglobin is specified by a single gene. Unique sequence DNA probes were isolated from the cloned gene and used to test for the presence of the human myoglobin gene in a series of human rodent somatic cell hybrids containing various complements of human chromosomes. The myoglobin gene cosegregated with human chromosome 22. Somatic cell hybrids containing translocation chromosomes carrying part of chromosome 22 were used to locate the myoglobin gene to the region 22q11----22q13. The myoglobin gene is therefore not linked to the alpha-globin gene cluster on chromosome 16 or the beta-globin cluster on chromosome 11, and represents a third dispersed globin locus in the human genome.

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Year:  1984        PMID： 6326055      PMCID： PMC318741          DOI： 10.1093/nar/12.7.3235

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  32 in total

1.  Phylogenetic origins and adaptive evolution of avian and mammalian haemoglobin genes.

Authors:  J Czelusniak; M Goodman; D Hewett-Emmett; M L Weiss; P J Venta; R E Tashian
Journal:  Nature       Date:  1982-07-15       Impact factor: 49.962

2.  Localization of the human alpha-globin gene cluster to the short arm of chromosome 16 (16p12-16pter) by hybridization in situ.

Authors:  P Barton; S Malcolm; C Murphy; M A Ferguson-Smith
Journal:  J Mol Biol       Date:  1982-04-05       Impact factor: 5.469

3.  A reliable method for the recovery of DNA fragments from agarose and acrylamide gels.

Authors:  G Dretzen; M Bellard; P Sassone-Corsi; P Chambon
Journal:  Anal Biochem       Date:  1981-04       Impact factor: 3.365

4.  A human X-linked antigen defined by a monoclonal antibody.

Authors:  P Goodfellow; G Banting; R Levy; S Povey; A McMichael
Journal:  Somatic Cell Genet       Date:  1980-11

5.  Assignment of the genes for human lambda immunoglobulin chains to chromosome 22.

Authors:  J Erikson; J Martinis; C M Croce
Journal:  Nature       Date:  1981-11-12       Impact factor: 49.962

6.  The structure and evolution of the human beta-globin gene family.

Authors:  A Efstratiadis; J W Posakony; T Maniatis; R M Lawn; C O'Connell; R A Spritz; J K DeRiel; B G Forget; S M Weissman; J L Slightom; A E Blechl; O Smithies; F E Baralle; C C Shoulders; N J Proudfoot
Journal:  Cell       Date:  1980-10       Impact factor: 41.582

7.  Cytogenetic studies on African Burkitt's lymphoma cell lines: t(8;14), t(2;8) and t(8;22) translocations.

Authors:  A Bernheim; R Berger; G Lenoir
Journal:  Cancer Genet Cytogenet       Date:  1981-06

8.  Chromosomal localization of human cellular homologues of two viral oncogenes.

Authors:  N Heisterkamp; J Groffen; J R Stephenson; N K Spurr; P N Goodfellow; E Solomon; B Carritt; W F Bodmer
Journal:  Nature       Date:  1982-10-21       Impact factor: 49.962

9.  A human cell-surface antigen defined by a monoclonal antibody and controlled by a gene on chromosome 12.

Authors:  P W Andrews; B B Knowles; P N Goodfellow
Journal:  Somatic Cell Genet       Date:  1981-07

10.  DNA sequence variants in the G gamma-, A gamma-, delta- and beta-globin genes of man.

Authors:  A J Jeffreys
Journal:  Cell       Date:  1979-09       Impact factor: 41.582
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  3 in total

1.  Profile of Alec J. Jeffreys.

Authors:  Nick Zagorski
Journal:  Proc Natl Acad Sci U S A       Date:  2006-06-05       Impact factor: 11.205

Review 2.  Human chromosome 22.

Authors:  J C Kaplan; A Aurias; C Julier; M Prieur; M F Szajnert
Journal:  J Med Genet       Date:  1987-02       Impact factor: 6.318

3.  A linkage and physical map of chromosome 22, and some applications to gene mapping.

Authors:  C Julier; G M Lathrop; A Reghis; M F Szajnert; J M Lalouel; J C Kaplan
Journal:  Am J Hum Genet       Date:  1988-02       Impact factor: 11.025
  3 in total

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