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Literature DB >> 6792721

A human cell-surface antigen defined by a monoclonal antibody and controlled by a gene on chromosome 12.

P W Andrews, B B Knowles, P N Goodfellow.

Abstract

A murine monoclonal antibody 602-29, subclass IgG1, that recognizes an antigenic determinant expressed by most human cells is described. Immunoprecipitation and sodium dodecyl sulfate-gel electrophoresis analysis indicate that the antigenic determinant is carried by a protein with an apparent molecular weight of 21,000. The antigen is expressed by human-mouse somatic cell hybrids, and analysis of segregants that have lost human chromosomes indicates that the gene controlling expression of the 602-29 antigen is on chromosome 12.

Entities: Chemical Gene Species

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Year: 1981 PMID： 6792721 DOI： 10.1007/BF01542988

Source DB: PubMed Journal: Somatic Cell Genet ISSN： 0098-0366

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Cited

14 in total

1. Anti-CD9 antibodies augment neutrophil adherence to endothelium.

Authors: K D Forsyth
Journal: Immunology Date: 1991-02 Impact factor: 7.397

2. Distinct roles for tetraspanins CD9, CD63 and CD81 in the formation of multinucleated giant cells.

Authors: Varadarajan Parthasarathy; Francine Martin; Adrian Higginbottom; Helen Murray; Gregory W Moseley; Robert C Read; Gorakh Mal; Rachel Hulme; Peter N Monk; Lynda J Partridge
Journal: Immunology Date: 2009-06 Impact factor: 7.397

3. Assignment of the human CD9 gene to chromosome 12 (region P13) by use of human specific DNA probes.

Authors: P Benoit; M S Gross; P Frachet; J Frézal; G Uzan; C Boucheix; V C Nguyen
Journal: Hum Genet Date: 1991-01 Impact factor: 4.132

4. Genetics and biochemistry of collagen binding-triggered glandular differentiation in a human colon carcinoma cell line.

Authors: M Pignatelli; W F Bodmer
Journal: Proc Natl Acad Sci U S A Date: 1988-08 Impact factor: 11.205

A human cell-surface antigen defined by a monoclonal antibody and controlled by a gene on chromosome 12.

1. Anti-CD9 antibodies augment neutrophil adherence to endothelium.

2. Distinct roles for tetraspanins CD9, CD63 and CD81 in the formation of multinucleated giant cells.

3. Assignment of the human CD9 gene to chromosome 12 (region P13) by use of human specific DNA probes.

4. Genetics and biochemistry of collagen binding-triggered glandular differentiation in a human colon carcinoma cell line.

5. Expression of human CD antigens, including CD1 and CD25, by human x mouse interlineage leukaemia hybrids.

6. Surface antigens of human embryonic stem cells: changes upon differentiation in culture.

7. Testicular Germ Cell Tumors: A Paradigm for the Successful Treatment of Solid Tumor Stem Cells.

8. Cooperative role for tetraspanins in adhesin-mediated attachment of bacterial species to human epithelial cells.

9. The human myoglobin gene: a third dispersed globin locus in the human genome.

10. Preparation of fibroblast-free cytotrophoblast cultures utilizing differential expression of the CD9 antigen.