Literature DB >> 6323937

Coma and neuropathy after ingestion of herbal laxative containing podophyllin.

G J Dobb, R H Edis.   

Abstract

A case of poisoning caused by an excessive dose of herbal laxative tablets is reported. The patient's symptoms included coma and prolonged peripheral neuropathy. The clinical features were characteristic of podophyllin poisoning. Podophyllin was a component of the laxative tablets, but the container gave no indication of their potential toxicity. Methods of reducing the risk of inadvertent poisoning by herbal remedies are suggested.

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Year:  1984        PMID: 6323937     DOI: 10.5694/j.1326-5377.1984.tb108174.x

Source DB:  PubMed          Journal:  Med J Aust        ISSN: 0025-729X            Impact factor:   7.738


  6 in total

Review 1.  Podophyllin office therapy against condyloma should be abandoned.

Authors:  G von Krogh; E Longstaff
Journal:  Sex Transm Infect       Date:  2001-12       Impact factor: 3.519

2.  The extremes in orthopaedics! Whom to blame?

Authors:  Laxman Rijal; Gopal Sagar; Tahir Ansari; Ramakant Kumar; Sukesh Rao; Ramprasad Kancherla
Journal:  Musculoskelet Surg       Date:  2012-06-27

3.  Neuropathy due to podophyllin intoxication.

Authors:  S O'Mahony; C Keohane; J Jacobs; D O'Riordain; M Whelton
Journal:  J Neurol       Date:  1990-04       Impact factor: 4.849

4.  Toxicity and neuropharmacological effects of elenine.

Authors:  Eduardo Navarro; S J Alonso; R Navarro
Journal:  Evid Based Complement Alternat Med       Date:  2011-05-26       Impact factor: 2.629

5.  Alleviation of podophyllotoxin toxicity using coexisting flavonoids from Dysosma versipellis.

Authors:  Juan Li; Hua Sun; Lu Jin; Wei Cao; Jin Zhang; Chong-Yi Guo; Ke Ding; Cheng Luo; Wen-Cai Ye; Ren-Wang Jiang
Journal:  PLoS One       Date:  2013-08-21       Impact factor: 3.240

6.  Metabolic map of the antiviral drug podophyllotoxin provides insights into hepatotoxicity.

Authors:  Dongxue Sun; Xiaoxia Gao; Qiao Wang; Kristopher W Krausz; Zhongze Fang; Youbo Zhang; Cen Xie; Frank J Gonzalez
Journal:  Xenobiotica       Date:  2021-08-09       Impact factor: 1.997

  6 in total

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