Literature DB >> 2162382

Neuropathy due to podophyllin intoxication.

S O'Mahony1, C Keohane, J Jacobs, D O'Riordain, M Whelton.   

Abstract

A 22-year-old man developed a severe sensorimotor neuropathy following ingestion of podophyllin, which had been prescribed for genital condylomata. The initial toxic symptoms were vomiting and diarrhoea, followed by peripheral neuropathy. The neuropathy was still present 18 months later. Nerve conduction studies and sural nerve biopsy confirmed the presence of axonal degeneration.

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Year:  1990        PMID: 2162382     DOI: 10.1007/BF00314673

Source DB:  PubMed          Journal:  J Neurol        ISSN: 0340-5354            Impact factor:   4.849


  25 in total

1.  Correlation of tubulin-binding and antitumor activities of podophyllotoxin analogs.

Authors:  J K Kelleher
Journal:  Cancer Treat Rep       Date:  1978-10

2.  A case of podophyllum poisoning with involvement of the nervous system.

Authors:  A N CLARK; M J PARSONAGE
Journal:  Br Med J       Date:  1957-11-16

3.  Discovery of podophyllum resin.

Authors:  S J ZAKON
Journal:  AMA Arch Derm Syphilol       Date:  1952-05

Review 4.  Podophyllin treatment of hairy tongue: a warning.

Authors:  J F Hasler; S M Standish
Journal:  J Am Dent Assoc       Date:  1969-03       Impact factor: 3.634

Review 5.  Podophyllum toxicity: a report of a fatal case and a review of the literature.

Authors:  D E Cassidy; J Drewry; J P Fanning
Journal:  J Toxicol Clin Toxicol       Date:  1982-03

6.  Podophyllin poisoning. Systemic toxicity following cutaneous application.

Authors:  G E Slater; B H Rumack; R G Peterson
Journal:  Obstet Gynecol       Date:  1978-07       Impact factor: 7.661

7.  [Severe generalized poisoning following local application of podophyllin alcohol in pointed condyloma].

Authors:  C G Schirren
Journal:  Hautarzt       Date:  1966-07       Impact factor: 0.751

8.  Podophyllum toxicity: case report and literature review.

Authors:  L M Moher; S A Maurer
Journal:  J Fam Pract       Date:  1979-08       Impact factor: 0.493

9.  Coma and neuropathy after ingestion of herbal laxative containing podophyllin.

Authors:  G J Dobb; R H Edis
Journal:  Med J Aust       Date:  1984-04-14       Impact factor: 7.738

10.  Qualitative and quantitative morphology of human sural nerve at different ages.

Authors:  J M Jacobs; S Love
Journal:  Brain       Date:  1985-12       Impact factor: 13.501

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