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Literature DB >> 631897

Detection of cholera enterotoxin activity in suckling hamsters.

T Takeda, Y Takeda, T Miwatani, N Ohtomo.

Abstract

For detection of cholera enterotoxin activity, suckling hamster, mouse, and rat models were compared. It was found that not only suckling mice but also suckling rats and hamsters were sensitive to cholera enterotoxin. Among these models, suckling hamsters were the most sensitive and gave positive results with about 1/100 the cholera toxin seen in suckling mice and rats.

Entities: Species

Mesh：

Substances：
Cholera Toxin

Year: 1978 PMID： 631897 PMCID： PMC414145 DOI： 10.1128/iai.19.2.752-754.1978

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

16 in total

1. Enterotoxicity of bacteria-free culture-filtrate of Vibrio cholerae.

Authors: S N DE
Journal: Nature Date: 1959-05-30 Impact factor: 49.962

2. Role of cholera a toxin in experimental cholera.

Authors: N K DUTTA; M V PANSE; D R KULKARNI
Journal: J Bacteriol Date: 1959-10 Impact factor: 3.490

3. Involvement of nicotinamide adenine dinucleotide in the action of cholera toxin in vitro.

Authors: D M Gill
Journal: Proc Natl Acad Sci U S A Date: 1975-06 Impact factor: 11.205

4. Intestinal fluid accumulation induced by oral challenge with Vibrio cholerae or cholera toxin in infant mice.

Authors: V Baselski; R Briggs; C Parker
Journal: Infect Immun Date: 1977-03 Impact factor: 3.441

5. Toxin from the culture filtrate of Shigella dysenteriae that causes morphological changes in Chinese hamster ovary cells and is distinct from the neurotoxin.

Authors: Y Takeda; K Okamoto; T Miwatani
Journal: Infect Immun Date: 1977-11 Impact factor: 3.441

6. Detection of heat-labile Escherichia coli enterotoxin with the use of adrenal cells in tissue culture.

Authors: S T Donta; H W Moon; S C Whipp
Journal: Science Date: 1974-01-25 Impact factor: 47.728

7. Isolation of a factor causing morphological changes of chinese hamster ovary cells from the culture filtrate of Vibrio parahaemolyticus.

Authors: T Honda; M Shimizu; Y Takeda; T Miwatani
Journal: Infect Immun Date: 1976-10 Impact factor: 3.441

8. Isolation of skin permeability factors from culture filtrates of Salmonella typhimurium.

Authors: P D Sandefur; J W Peterson
Journal: Infect Immun Date: 1976-09 Impact factor: 3.441

9. The Syrian hamster: a reproducible model for studying changes in intestinal fluid secretion in response to enterotoxin challenge.

Authors: A Lepot; J G Banwell
Journal: Infect Immun Date: 1976-11 Impact factor: 3.441

10. Cyclic adenosine monophosphate and alteration of Chinese hamster ovary cell morphology: a rapid, sensitive in vitro assay for the enterotoxins of Vibrio cholerae and Escherichia coli.

Authors: R L Guerrant; L L Brunton; T C Schnaitman; L I Rebhun; A G Gilman
Journal: Infect Immun Date: 1974-08 Impact factor: 3.441

5 in total

1. Purification and partial characterization of heat-stable enterotoxin of enterotoxigenic Escherichia coli.

Authors: Y Takeda; T Takeda; T Yano; K Yamamoto; T Miwatani
Journal: Infect Immun Date: 1979-09 Impact factor: 3.441

2. Failure of chlorpromazine to inhibit fluid accumulation caused by Escherichia coli heat-stable enterotoxin in suckling mice.

Authors: T Takeda; T Honda; Y Takeda; T Miwatani
Journal: Infect Immun Date: 1981-05 Impact factor: 3.441