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Literature DB >> 6315023

HR 810, a new parenteral cephalosporin with a broad antibacterial spectrum.

G Seibert, N Klesel, M Limbert, E Schrinner, K Seeger, I Winkler, R Lattrell, J Blumbach, W Dürckheimer, K Fleischmann.

Abstract

3-[(2,3-Cyclopenteno-1-pyridinium)-methyl]-7-[2-syn-methoximino-2-(2-aminothiazol-4-yl)-acetamido]-ceph-3-em-4-carboxylate (HR 810) is a new cephalosporin derivative with an extremely broad antimicrobial spectrum. It is active against all bacterial species of clinical relevance, including strains which are frequently resistant towards cephalosporins of the third generation.

Entities: Chemical

Mesh：

Substances：

Year: 1983 PMID： 6315023 DOI： 10.1002/chin.198350201

Source DB: PubMed Journal: Arzneimittelforschung ISSN： 0004-4172

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Cited

19 in total

1. In vitro effects of beta-lactams combined with beta-lactamase inhibitors against methicillin-resistant Staphylococcus aureus.

Authors: S Kobayashi; S Arai; S Hayashi; T Sakaguchi
Journal: Antimicrob Agents Chemother Date: 1989-03 Impact factor: 5.191

2. Pharmacokinetics of cefpirome (HR 810), a new cephalosporin derivative administered intramuscularly and intravenously to healthy volunteers.

Authors: L Maass; V Malerczyk; M Verho
Journal: Infection Date: 1987 May-Jun Impact factor: 3.553

3. Pharmacokinetic properties of the new cephalosporin antibiotic HR 810 in animals.

Authors: N Klesel; K Seeger
Journal: Infection Date: 1983 Nov-Dec Impact factor: 3.553

4. Antimicrobial activity of HR810 against 419 strict anaerobic bacteria.

Authors: R N Jones; E H Gerlach
Journal: Antimicrob Agents Chemother Date: 1985-03 Impact factor: 5.191

5. In vitro activity of HR 810, a new cephalosporin.

Authors: M A Bertram; D A Bruckner; L S Young
Journal: Antimicrob Agents Chemother Date: 1984-08 Impact factor: 5.191

6. Prevalence and antibiotic sensitivity of Danish versus other European bacterial isolates from intensive care and hematology/oncology units.

Authors: A Fomsgaard; N Høiby; H M Friis; B Gahrn-Hansen; H J Kolmos; P Schouenborg; B Korsager; M Tvede; E Gutschik; A Bremmelgaard
Journal: Eur J Clin Microbiol Infect Dis Date: 1995-04 Impact factor: 3.267

HR 810, a new parenteral cephalosporin with a broad antibacterial spectrum.

1. In vitro effects of beta-lactams combined with beta-lactamase inhibitors against methicillin-resistant Staphylococcus aureus.

2. Pharmacokinetics of cefpirome (HR 810), a new cephalosporin derivative administered intramuscularly and intravenously to healthy volunteers.

3. Pharmacokinetic properties of the new cephalosporin antibiotic HR 810 in animals.

4. Antimicrobial activity of HR810 against 419 strict anaerobic bacteria.

5. In vitro activity of HR 810, a new cephalosporin.

6. Prevalence and antibiotic sensitivity of Danish versus other European bacterial isolates from intensive care and hematology/oncology units.

7. Dose linearity testing of intravenous cefpirome (HR 810), a novel cephalosporin derivate.

8. Single and multiple dose pharmacokinetics of intravenous cefpirome (HR 810), a novel cephalosporin derivative.

9. Determination of cefpirome (HR 810) in serum and urine.

10. Renal tolerance of cefpirome (HR 810), a new cephalosporin antibiotic.