Literature DB >> 3372025

Determination of cefpirome (HR 810) in serum and urine.

M Uihlein1, N Klesel, K Seeger.   

Abstract

Cefpirome (HR 810) is a new cephalosporin under clinical investigation. Specific and sensitive HPLC- and agar-diffusion methods were developed for the determination of serum- and urine concentrations. The methods are fully validated according to the IFCC Recommendations on Quality Control in Clinical Chemistry. In order to demonstrate the usefulness of both methods, pharmacokinetic profiles of cefpirome after 1 g i.v. administration to human volunteers are presented.

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Year:  1988        PMID: 3372025     DOI: 10.1007/bf01644323

Source DB:  PubMed          Journal:  Infection        ISSN: 0300-8126            Impact factor:   3.553


  4 in total

1.  A new biometrical procedure for testing the equality of measurements from two different analytical methods. Application of linear regression procedures for method comparison studies in clinical chemistry, Part I.

Authors:  H Passing
Journal:  J Clin Chem Clin Biochem       Date:  1983-11

2.  International Federation of Clinical Chemistry. Committee on Standards. Expert Panel on Nomenclature and Principles of Quality Control in Clinical Chemistry. Approved recommendation (1978) on quality control in clinical chemistry. Part 2. Assesment of analytical methods for routine use.

Authors:  J Büttner; R Borth; J H Boutwell; P M Broughton; R C Bowyer
Journal:  Clin Chim Acta       Date:  1979-10-15       Impact factor: 3.786

3.  Single and multiple dose pharmacokinetics of intravenous cefpirome (HR 810), a novel cephalosporin derivative.

Authors:  V Malerczyk; L Maass; M Verho; P Hajdú; N Klesel; R Rangoonwala
Journal:  Infection       Date:  1987 May-Jun       Impact factor: 3.553

4.  HR 810, a new parenteral cephalosporin with a broad antibacterial spectrum.

Authors:  G Seibert; N Klesel; M Limbert; E Schrinner; K Seeger; I Winkler; R Lattrell; J Blumbach; W Dürckheimer; K Fleischmann
Journal:  Arzneimittelforschung       Date:  1983
  4 in total
  2 in total

Review 1.  Cefpirome clinical pharmacokinetics.

Authors:  L C Strenkoski; D E Nix
Journal:  Clin Pharmacokinet       Date:  1993-10       Impact factor: 6.447

2.  New Stability Indicating RP-HPLC Method for the Estimation of Cefpirome Sulphate in Bulk and Pharmaceutical Dosage Forms.

Authors:  Kareti Srinivasa Rao; Keshar Nargesh Kumar; Datta Joydeep
Journal:  Sci Pharm       Date:  2011-08-07
  2 in total

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