Literature DB >> 6311731

The IgG subclass responses of human lymphocytes to B-cell activators.

L Walker, G D Johnson, I C MacLennan.   

Abstract

The induction of IgG synthesis by normal human lymphocytes in response to a range of B-cell activators has been studied by indirect cytoplasmic immunofluorescence using monoclonal antibodies to the four IgG subclasses. Considerable variation was found between cells from different donors tested with the same activator but the following trends were observed:- Epstein-Barr virus and Branhamella catarrhalis induced a predominantly IgG3 response, whereas the most prevalent cells in cultures stimulated with lipopolysaccharide and Staph. aureus were IgG2-positive; the subclass distribution obtained with pokeweed mitogen resembled that found in normal serum (IgG1 greater than 2 greater than 3 greater than 4).

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6311731      PMCID： PMC1454335     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  6 in total

1.  Monoclonal antibodies (McAbs) to determinants on human gamma chains: properties of antibodies showing subclass restriction or subclass specificity.

Authors:  J Lowe; P Bird; D Hardie; R Jefferis; N R Ling
Journal:  Immunology       Date:  1982-10       Impact factor: 7.397

2.  Determination of IgG subclasses and Gm allotypes in culture supernatants of pokeweed mitogen-stimulated human blood lymphocytes.

Authors:  A Morell; E Van Loghem; M Nef; L Theilkaes; F Skvaril
Journal:  J Immunol       Date:  1981-09       Impact factor: 5.422

3.  Fading of immunofluorescence during microscopy: a study of the phenomenon and its remedy.

Authors:  G D Johnson; R S Davidson; K C McNamee; G Russell; D Goodwin; E J Holborow
Journal:  J Immunol Methods       Date:  1982-12-17       Impact factor: 2.303

Review 4.  Human IgG subclasses in health and disease. (A review). Part II.

Authors:  F Shakib; D R Stanworth
Journal:  Ric Clin Lab       Date:  1980 Oct-Dec

5.  Natural infection of man with group A streptococci. Levels; restriction in class, subclass, and type; and clonal appearance of polysaccharide-group-specific antibodies.

Authors:  W F Riesen; F Skvaril; D G Braun
Journal:  Scand J Immunol       Date:  1976       Impact factor: 3.487

6.  Studies on human antibodies. VI. Selective variations in subgroup composition and genetic markers.

Authors:  W J Yount; M M Dorner; H G Kunkel; E A Kabat
Journal:  J Exp Med       Date:  1968-03-01       Impact factor: 14.307
  6 in total
  17 in total

1.  Immunoglobulin gene rearrangements and deletions in human Epstein-Barr virus-transformed cell lines producing different IgG and IgA subclasses.

Authors:  C F Webb; M D Cooper; P D Burrows; J A Griffin
Journal:  Proc Natl Acad Sci U S A       Date:  1985-08       Impact factor: 11.205

2.  Immunoglobulin subclass distribution of human anti-carbohydrate antibodies: aberrant pattern in IgA-deficient donors.

Authors:  L Hammarström; M A Persson; C I Smith
Journal:  Immunology       Date:  1985-04       Impact factor: 7.397

3.  Regulation of human IgG subclass production by cytokines: human IgG subclass production enhanced differentially by interleukin-6.

Authors:  Y Kawano; T Noma; K Kou; I Yoshizawa; J Yata
Journal:  Immunology       Date:  1995-02       Impact factor: 7.397

4.  Subclasses of IgG on the surface of human lymphocytes: a study with monoclonal antibodies.

Authors:  L Partridge; R Jefferis; D Hardie; N R Ling; P Richardson
Journal:  Clin Exp Immunol       Date:  1984-04       Impact factor: 4.330

5.  An antigenic study of human plasma cells in normal tissue and in myeloma: identification of a novel plasma cell associated antigen.

Authors:  P D Nathan; L Walker; D Hardie; P Richardson; M Khan; G D Johnson; N R Ling
Journal:  Clin Exp Immunol       Date:  1986-07       Impact factor: 4.330

6.  Analysis of IgG subclass production in cell cultures from IgA deficient patients and in normal controls as a function of age.

Authors:  G Luzi; H Kubagawa; M J Crain; M D Cooper
Journal:  Clin Exp Immunol       Date:  1986-08       Impact factor: 4.330

7.  Immunoglobulin G (IgG) and IgA subclass pattern of human antibodies to Shigella flexneri and Salmonella serogroup B and D lipopolysaccharide O antigens.

Authors:  M A Persson; E Ekwall; L Hammarström; A A Lindberg; C I Smith
Journal:  Infect Immun       Date:  1986-06       Impact factor: 3.441

8.  Characterization of anti-liver kidney microsomal antibody in childhood autoimmune chronic active hepatitis: evidence for IgG1 subclass restriction, polyclonality and non cross-reactivity with hepatocyte surface antigens.

Authors:  M Peakman; A Lobo-Yeo; G Mieli-Vergani; E T Davies; A P Mowat; D Vergani
Journal:  Clin Exp Immunol       Date:  1987-09       Impact factor: 4.330

9.  Maternal antibodies and acquired serological response to Moraxella catarrhalis in children determined by an enzyme-linked immunosorbent assay.

Authors:  T Ejlertsen; E Thisted; P A Ostergaard; J Renneberg
Journal:  Clin Diagn Lab Immunol       Date:  1994-07

10.  IgG-subclass expression of anti-DNA and anti-ribonucleoprotein autoantibodies in human malaria.

Authors:  M Zouali; P Druilhe; A Eyquem
Journal:  Clin Exp Immunol       Date:  1986-11       Impact factor: 4.330
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.