Literature DB >> 6308645

A transmissible retrovirus expressing human hypoxanthine phosphoribosyltransferase (HPRT): gene transfer into cells obtained from humans deficient in HPRT.

A D Miller, D J Jolly, T Friedmann, I M Verma.   

Abstract

A cDNA corresponding to the human gene for hypoxanthine phosphoribosyltransferase (HPRT; IMP:pyrophosphate phosphoribosyltransferase, EC 2.4.2.8) has been ligated into murine retroviral vectors such that it is under the transcriptional control of viral long terminal repeats. Transfection of HPRT- cells followed by superinfection with various helper viruses has led to the rescue of chimeric virus capable of transmitting the HPRT+ phenotype to HPRT- rodent or human cells. These genetically transformed cells contain authentic human HPRT at levels similar to normal HPRT+ cells.

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Year:  1983        PMID： 6308645      PMCID： PMC384113          DOI： 10.1073/pnas.80.15.4709

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  32 in total

1.  A direct measurement of the radiation sensitivity of normal mouse bone marrow cells.

Authors:  J E TILL; E A McCULLOCH
Journal:  Radiat Res       Date:  1961-02       Impact factor: 2.841

2.  Transformation of mammalian cells by avian myelocytomatosis virus and avian erythroblastosis virus.

Authors:  K Quade
Journal:  Virology       Date:  1979-10-30       Impact factor: 3.616

3.  Synthesis of rabbit beta-globin in cultured monkey kidney cells following infection with a SV40 beta-globin recombinant genome.

Authors:  R C Mulligan; B H Howard; P Berg
Journal:  Nature       Date:  1979-01-11       Impact factor: 49.962

Review 4.  The HPRT locus.

Authors:  C T Caskey; G D Kruh
Journal:  Cell       Date:  1979-01       Impact factor: 41.582

5.  Human and mouse hypoxanthine-guanine phosphoribosyltransferase: dimers and tetramers.

Authors:  G G Johnson; L R Eisenberg; B R Migeon
Journal:  Science       Date:  1979-01-12       Impact factor: 47.728

6.  Formation of infectious progeny virus after insertion of herpes simplex thymidine kinase gene into DNA of an avian retrovirus.

Authors:  K Shimotohno; H M Temin
Journal:  Cell       Date:  1981-10       Impact factor: 41.582

7.  High efficiency transformation by direct microinjection of DNA into cultured mammalian cells.

Authors:  M R Capecchi
Journal:  Cell       Date:  1980-11       Impact factor: 41.582

8.  Structure of Moloney murine leukemia viral DNA: nucleotide sequence of the 5' long terminal repeat and adjacent cellular sequences.

Authors:  C Van Beveren; J G Goddard; A Berns; I M Verma
Journal:  Proc Natl Acad Sci U S A       Date:  1980-06       Impact factor: 11.205

9.  Measurement of the sequence complexity of cloned Moloney murine leukemia virus 60 to 70S RNA: evidence for a haploid genome.

Authors:  H Fan; M Paskind
Journal:  J Virol       Date:  1974-09       Impact factor: 5.103

10.  Isolation and characterization of a full-length expressible cDNA for human hypoxanthine phosphoribosyl transferase.

Authors:  D J Jolly; H Okayama; P Berg; A C Esty; D Filpula; P Bohlen; G G Johnson; J E Shively; T Hunkapillar; T Friedmann
Journal:  Proc Natl Acad Sci U S A       Date:  1983-01       Impact factor: 11.205
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  53 in total

Review 1.  Virus-based gene delivery systems.

Authors:  Cathryn Mah; Barry J Byrne; Terence R Flotte
Journal:  Clin Pharmacokinet       Date:  2002       Impact factor: 6.447

2.  Herpes simplex virus-mediated human hypoxanthine-guanine phosphoribosyltransferase gene transfer into neuronal cells.

Authors:  T D Palella; L J Silverman; C T Schroll; F L Homa; M Levine; W N Kelley
Journal:  Mol Cell Biol       Date:  1988-01       Impact factor: 4.272

Review 3.  Genotoxicity of retroviral hematopoietic stem cell gene therapy.

Authors:  Grant D Trobridge
Journal:  Expert Opin Biol Ther       Date:  2011-03-07       Impact factor: 4.388

4.  Revertants of v-fos-transformed rat fibroblasts: suppression of transformation is dominant.

Authors:  R Wisdom; I M Verma
Journal:  Mol Cell Biol       Date:  1990-11       Impact factor: 4.272

Review 5.  Retroviral vectors: from cancer viruses to therapeutic tools.

Authors:  A Dusty Miller
Journal:  Hum Gene Ther       Date:  2014-12       Impact factor: 5.695

Review 6.  Gene transfer into the nervous system.

Authors:  X O Breakefield; A I Geller
Journal:  Mol Neurobiol       Date:  1987       Impact factor: 5.590

7.  Characterization of a retrovirus shuttle vector capable of either proviral integration or extrachromosomal replication in mouse cells.

Authors:  S A Berger; A Bernstein
Journal:  Mol Cell Biol       Date:  1985-02       Impact factor: 4.272

8.  Generation of helper-free amphotropic retroviruses that transduce a dominant-acting, methotrexate-resistant dihydrofolate reductase gene.

Authors:  A D Miller; M F Law; I M Verma
Journal:  Mol Cell Biol       Date:  1985-03       Impact factor: 4.272

9.  H-2Ld antigen encoded by a recombinant retrovirus genome is expressed on the surface of infected cells.

Authors:  J H Weis; C S Reiss; R C Mulligan; S J Burakoff; J G Seidman
Journal:  Mol Cell Biol       Date:  1985-06       Impact factor: 4.272

Review 10.  Human Cardiac Gene Therapy.

Authors:  Kiyotake Ishikawa; Thomas Weber; Roger J Hajjar
Journal:  Circ Res       Date:  2018-08-17       Impact factor: 17.367
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