| Literature DB >> 215915 |
R C Mulligan, B H Howard, P Berg.
Abstract
Rabbit beta-globin complementary DNA (cDNA) has been inserted into SV40 DNA in place of the gene coding for the virus' major capsid protein, VP1. The recombinant genome, SVGT5-RabetaG, multiplies efficiently in CV1 monkey kidney cell cultures and is transcribed to yield cytoplasmic, polyadenylated hybrid mRNAs containing the beta-globin coding sequence. Cells propagating SVGT5-RabetaG produce substantial quantities of rabbit beta-globin polypeptide.Entities:
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Year: 1979 PMID: 215915 DOI: 10.1038/277108a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962