Literature DB >> 569362

Human and mouse hypoxanthine-guanine phosphoribosyltransferase: dimers and tetramers.

G G Johnson, L R Eisenberg, B R Migeon.   

Abstract

Human and mouse hypoxanthine-guanine phosphoribosyltransferase subunits combine to form an active heteropolymer. Dimers form the basic subunit structure of the enzymes, yet the dimers can readily associate to form tetramers. The equilibrium between dimers and tetramers is significantly influenced by the ionic strength of the enzyme solvent.

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Year:  1979        PMID： 569362     DOI： 10.1126/science.569362

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  18 in total

1.  Expression of retrovirally transduced genes in primary cultures of adult rat hepatocytes.

Authors:  J A Wolff; J K Yee; H F Skelly; J C Moores; J G Respess; T Friedmann; H Leffert
Journal:  Proc Natl Acad Sci U S A       Date:  1987-05       Impact factor: 11.205

2.  Partial purification and characterization of the mRNA for human thymidine kinase and hypoxanthine/guanine phosphoribosyltransferase.

Authors:  P F Lin; M Yamaizumi; P D Murphy; A Egg; F H Ruddle
Journal:  Proc Natl Acad Sci U S A       Date:  1982-07       Impact factor: 11.205

3.  Comparison of the properties of the alcohol dehydrogenases from wild-type and mutant Chinese hamster somatic cells.

Authors:  B G Talbot; J P Thirion
Journal:  Biochem Genet       Date:  1979-10       Impact factor: 1.890

4.  Genetic evidence for the inactivation of a human autosomal locus attached to an inactive X chromosome.

Authors:  T Mohandas; R S Sparkes; L J Shapiro
Journal:  Am J Hum Genet       Date:  1982-09       Impact factor: 11.025

5.  The organization of the human HPRT gene.

Authors:  S H Kim; J C Moores; D David; J G Respess; D J Jolly; T Friedmann
Journal:  Nucleic Acids Res       Date:  1986-04-11       Impact factor: 16.971

6.  Isolation of a genomic clone partially encoding human hypoxanthine phosphoribosyltransferase.

Authors:  D J Jolly; A C Esty; H U Bernard; T Friedmann
Journal:  Proc Natl Acad Sci U S A       Date:  1982-08       Impact factor: 11.205

7.  Human hypoxanthine-guanine phosphoribosyltransferase. Demonstration of structural variants in lymphoblastoid cells derived from patients with a deficiency of the enzyme.

Authors:  J M Wilson; B W Baugher; P M Mattes; P E Daddona; W N Kelley
Journal:  J Clin Invest       Date:  1982-03       Impact factor: 14.808

8.  Gene expression from transcriptionally disabled retroviral vectors.

Authors:  J K Yee; J C Moores; D J Jolly; J A Wolff; J G Respess; T Friedmann
Journal:  Proc Natl Acad Sci U S A       Date:  1987-08       Impact factor: 11.205

9.  Analysis of cDNA encoding the hypoxanthine-guanine phosphoribosyltransferase (HGPRTase) of Schistosoma mansoni; a putative target for chemotherapy.

Authors:  S P Craig; J H McKerrow; G R Newport; C C Wang
Journal:  Nucleic Acids Res       Date:  1988-07-25       Impact factor: 16.971

10.  Transformation with DNA from 5-azacytidine-reactivated X chromosomes.

Authors:  L Venolia; S M Gartler; E R Wassman; P Yen; T Mohandas; L J Shapiro
Journal:  Proc Natl Acad Sci U S A       Date:  1982-04       Impact factor: 11.205
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