Literature DB >> 6304630

Structure of mouse rRNA precursors. Complete sequence and potential folding of the spacer regions between 18S and 28S rRNA.

B Michot, J P Bachellerie, F Raynal.   

Abstract

We have determined the complete nucleotide sequence of the regions of mouse ribosomal RNA transcription unit which separate mature rRNA genes. These internal transcribed spacers (ITS) are excised from rRNA precursor during ribosome biosynthesis. ITS 1, between 18S and 5.8S rRNA genes, is 999 nucleotides long. ITS 2, between 5.8S and 28S rRNA genes, is 1089 nucleotides long. Both spacers are very rich in G + C, 70 and 74% respectively. Mouse sequences have been compared with the other available eukaryotes: while no homology is apparent with yeast or xenopus, mouse and rat ITS sequences have been largely conserved, with homologous segments interspersed with highly divergent tracts. Homology with rat is much more extensive for ITS 1 than for ITS 2. Tentative secondary structure models are proposed for the folding of these regions within rRNA precursor; they are closely related in mouse and rat.

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Year:  1983        PMID： 6304630      PMCID： PMC325970          DOI： 10.1093/nar/11.10.3375

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  42 in total

1.  Improved estimation of secondary structure in ribonucleic acids.

Authors:  I Tinoco; P N Borer; B Dengler; M D Levin; O C Uhlenbeck; D M Crothers; J Bralla
Journal:  Nat New Biol       Date:  1973-11-14

2.  The properties of O 6 -methylguanine in templates for RNA polymerase.

Authors:  L L Gerchman; D B Ludlum
Journal:  Biochim Biophys Acta       Date:  1973-05-10

3.  Salt-induced co-operative conformational change of a synthetic DNA: equilibrium and kinetic studies with poly (dG-dC).

Authors:  F M Pohl; T M Jovin
Journal:  J Mol Biol       Date:  1972-06-28       Impact factor: 5.469

4.  Possible relevance of O-6 alkylation of deoxyguanosine to the mutagenicity and carcinogenicity of nitrosamines and nitrosamides.

Authors:  A Loveless
Journal:  Nature       Date:  1969-07-12       Impact factor: 49.962

5.  Repair of O6-methylguanine in adapted Escherichia coli.

Authors:  P F Schendel; P E Robins
Journal:  Proc Natl Acad Sci U S A       Date:  1978-12       Impact factor: 11.205

Review 6.  Processing of RNA.

Authors:  R P Perry
Journal:  Annu Rev Biochem       Date:  1976       Impact factor: 23.643

7.  Conservation of the primary structure at the 3' end of 18S rRNA from eucaryotic cells.

Authors:  O Hagenbüchle; M Santer; J A Steitz; R J Mans
Journal:  Cell       Date:  1978-03       Impact factor: 41.582

8.  Mapping of the Xenopus laevis 5.8S rDNA by restriction and DNA sequencing.

Authors:  P G Boseley; A Tuyns; M L Birnstiel
Journal:  Nucleic Acids Res       Date:  1978-04       Impact factor: 16.971

9.  A comparison of the ribosomal DNA's of Xenopus laevis and Xenopus mulleri: the evolution of tandem genes.

Authors:  D D Brown; P C Wensink; E Jordan
Journal:  J Mol Biol       Date:  1972-01-14       Impact factor: 5.469

10.  Patterns of major divergence between the internal transcribed spacers of ribosomal DNA in Xenopus borealis and Xenopus laevis, and of minimal divergence within ribosomal coding regions.

Authors:  J C Furlong; B E Maden
Journal:  EMBO J       Date:  1983       Impact factor: 11.598
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  34 in total

1.  Complementarity between the mRNA 5' untranslated region and 18S ribosomal RNA can inhibit translation.

Authors:  S B Verrier; O Jean-Jean
Journal:  RNA       Date:  2000-04       Impact factor: 4.942

2.  Retroposons do jump: a B2 element recently integrated in an 18S rDNA gene.

Authors:  I Oberbäumer
Journal:  Nucleic Acids Res       Date:  1992-02-25       Impact factor: 16.971

3.  Nucleotide sequence of a 5.8S rDNA gene and of the internal transcribed spacers from Populus deltoides.

Authors:  R D'Ovidio
Journal:  Plant Mol Biol       Date:  1992-09       Impact factor: 4.076

4.  Modulation of RNA editing by functional nucleolar sequestration of ADAR2.

Authors:  Christopher L Sansam; K Sam Wells; Ronald B Emeson
Journal:  Proc Natl Acad Sci U S A       Date:  2003-11-11       Impact factor: 11.205

5.  Activation of double-stranded RNA dependent protein kinase by ribosomal RNA precursors.

Authors:  B Bottazzi; M Clayton; L Varesio
Journal:  Cytotechnology       Date:  1987-10       Impact factor: 2.058

6.  A conserved core structure in the 18-25S rRNA intergenic region from tobacco, Nicotiana rustica.

Authors:  K Venkateswarlu; R Nazar
Journal:  Plant Mol Biol       Date:  1991-08       Impact factor: 4.076

7.  Nucleotide sequence of the 17S-25S spacer region from rice rDNA.

Authors:  F Takaiwa; K Oono; M Sugiura
Journal:  Plant Mol Biol       Date:  1985-11       Impact factor: 4.076

8.  Sequence studies on the soybean chloroplast 16S-23S rDNA spacer region : Comparison with other angiosperm sequences and proposal of a generalized RNA secondary structure model for the intergenic regions.

Authors:  G de Lanversin; D T Pillay; B Jacq
Journal:  Plant Mol Biol       Date:  1987-01       Impact factor: 4.076

9.  GC balance in the internal transcribed spacers ITS 1 and ITS 2 of nuclear ribosomal RNA genes.

Authors:  R A Torres; M Ganal; V Hemleben
Journal:  J Mol Evol       Date:  1990-02       Impact factor: 2.395

10.  The external transcribed spacer and preceding region of Xenopus borealis rDNA: comparison with the corresponding region of Xenopus laevis rDNA.

Authors:  J C Furlong; J Forbes; M Robertson; B E Maden
Journal:  Nucleic Acids Res       Date:  1983-12-10       Impact factor: 16.971
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