Literature DB >> 6304023

Poly(ADP-ribosylation) of a DNA topoisomerase.

A M Ferro, N P Higgins, B M Olivera.   

Abstract

A DNA topoisomerase activity, copurifying with poly(ADP-ribose) synthetase from calf thymus, is greater than 95% inhibited if extensive poly(ADP-ribosylation) is allowed to occur. The inhibited DNA topoisomerase, which has drastically different elution properties on hydroxylapatite, can be reactivated by mild alkaline treatment. These results are consistent with a poly(ADP-ribosylation) of the DNA topoisomerase and covalent attachment of the poly(ADP-ribose) moieties to the topoisomerase by alkali-labile bonds.

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Year:  1983        PMID： 6304023

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  22 in total

Review 1.  Active cell death in hormone-dependent tissues.

Authors:  M P Tenniswood; R S Guenette; J Lakins; M Mooibroek; P Wong; J E Welsh
Journal:  Cancer Metastasis Rev       Date:  1992-09       Impact factor: 9.264

2.  Optimum DNA relaxation reaction conditions for calf thymus DNA-topoisomerase I are determined by specific enzyme features.

Authors:  S Coderoni; M Paparelli; G L Gianfranceschi
Journal:  Mol Biol Rep       Date:  1990-11       Impact factor: 2.316

3.  ADP-ribosyltransferase in isolated nuclei during the cell cycle of Physarum polycephalum.

Authors:  P Gröbner; P Loidl
Journal:  Biochem J       Date:  1985-11-15       Impact factor: 3.857

Review 4.  Poly-ADP-ribose polymerase: machinery for nuclear processes.

Authors:  Colin Thomas; Alexei V Tulin
Journal:  Mol Aspects Med       Date:  2013-04-25

5.  A dominant-negative mutant of human poly(ADP-ribose) polymerase affects cell recovery, apoptosis, and sister chromatid exchange following DNA damage.

Authors:  V Schreiber; D Hunting; C Trucco; B Gowans; D Grunwald; G De Murcia; J M De Murcia
Journal:  Proc Natl Acad Sci U S A       Date:  1995-05-23       Impact factor: 11.205

6.  Biological characterization of cyclothialidine, a new DNA gyrase inhibitor.

Authors:  N Nakada; H Shimada; T Hirata; Y Aoki; T Kamiyama; J Watanabe; M Arisawa
Journal:  Antimicrob Agents Chemother       Date:  1993-12       Impact factor: 5.191

7.  Glutamate regulates the activity of topoisomerase I in mouse cerebellum.

Authors:  Eldar Zehorai; Erez Eitan; Michal Hershfinkel; Israel Sekler; Esther Priel
Journal:  Mol Neurobiol       Date:  2008-11-04       Impact factor: 5.590

8.  DNA damage and cell death induced by 1,2-dibromo-3-chloropropane (DBCP) and structural analogs in monolayer culture of rat hepatocytes: 3-aminobenzamide inhibits the toxicity of DBCP.

Authors:  J A Holme; E J Søderlund; G Brunborg; M Låg; S D Nelson; E Dybing
Journal:  Cell Biol Toxicol       Date:  1991-10       Impact factor: 6.691

9.  Inhibition of poly(ADP-ribose) polymerase activity is insufficient to induce tetraploidy.

Authors:  C M Simbulan-Rosenthal; D S Rosenthal; R Luo; J H Li; J Zhang; M E Smulson
Journal:  Nucleic Acids Res       Date:  2001-02-01       Impact factor: 16.971

10.  Cloning and characterization of the gene for the somatic form of DNA topoisomerase I from Xenopus laevis.

Authors:  S D Pandit; R E Richard; R Sternglanz; D F Bogenhagen
Journal:  Nucleic Acids Res       Date:  1996-09-15       Impact factor: 16.971
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