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Literature DB >> 629858

Maintenance of biological and biochemical characteristics of human colorectal tumours during serial passage in immune-deprived mice.

Abstract

The effect of serial passage in immune-deprived mice on certain biological and biochemical parameters has been studied in a series of 6 human colorectal tumour xenografts. Histological integrity is maintained for up to 10 serial passages, together with production of epithelial mucins and carcinoembryonic antigen. Passaged tumours retain human lactate dehydrogenase and glucose-6-phosphate dehydrogenase isoenzyme patterns and a human chromosome constitution. The induction of a murine tumour has been identified in this system, and the importance of routine checks for the presence of human tissue during serial passage is stressed.

Entities: Disease Gene Species

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Year: 1978 PMID： 629858 PMCID： PMC2009589 DOI： 10.1038/bjc.1978.28

Source DB: PubMed Journal: Br J Cancer ISSN： 0007-0920 Impact factor: 7.640

19 in total

1. Development of a method for assessing the antitumor activity of chemotherapeutic agents using human tumor xenografts.

Authors: L M Cobb; B C Mitchley
Journal: Cancer Chemother Rep Date: 1974 Sep-Oct

2. Growth and antigenic properties of a biopsy-derived Burkitt's lymphoma in thymus-less (nude) mice.

Authors: C O Povlsen; P J Fialkow; E Klein; G Klein; J Rygaard; F Wiener
Journal: Int J Cancer Date: 1973-01-15 Impact factor: 7.396

3. Value of histochemical reactions for mucosubstances in the diagnosis of certain pathological conditions of the colon and rectum.

Authors: M I Filipe
Journal: Gut Date: 1969-07 Impact factor: 23.059

4. Carcinoembryonic antigenic activity of tissue extracts: a quantitative study of malignant and benign neoplasms, cirrhotic liver, normal adult and fetal organs.

Authors: S K Khoo; N L Warner; J T Lie; I R Mackay
Journal: Int J Cancer Date: 1973-05 Impact factor: 7.396

5. Cytogenetics of malignant lymphomas. Studies utilising a Giemsa-banding technique.

Authors: B R Reeves
Journal: Humangenetik Date: 1973-12-10

6. The therapeutic response of three human tumor lines maintained in immune-suppressed mice.

Authors: L Kopper; G G Steel
Journal: Cancer Res Date: 1975-10 Impact factor: 12.701

7. Effects of cytotoxic agents on TdR incorporation and growth delay in human colonic tumour xenografts.

Authors: P J Houghton; J A Houghton; D M Taylor
Journal: Br J Cancer Date: 1977-08 Impact factor: 7.640

8. Mucin histochemistry of mucous carcinomas of breast and colon and non-neoplastic breast epithelium.

Authors: D J Cooper
Journal: J Clin Pathol Date: 1974-04 Impact factor: 3.411

9. The growth kinetics of xenografts of human colorectal tumours in immune deprived mice.

Authors: R G Pickard; L M Cobb; G G Steel
Journal: Br J Cancer Date: 1975-01 Impact factor: 7.640

10. The behaviour of carcinoma of the large bowel in man following transplantation into immune deprived mice.

Authors: L M Cobb
Journal: Br J Cancer Date: 1973-11 Impact factor: 7.640

26 in total

1. Cell proliferation in human tumours growing in nude mice: renal cell carcinomas, larynx and hypopharynx carcinomas.

Authors: B Maurer-Schultze; I D Bassukas; M Böswald; M Harasim
Journal: J Cancer Res Clin Oncol Date: 1992 Impact factor: 4.553

2. Evaluation of Alternative In Vivo Drug Screening Methodology: A Single Mouse Analysis.

Authors: Brendan Murphy; Han Yin; John M Maris; E Anders Kolb; Richard Gorlick; C Patrick Reynolds; Min H Kang; Stephen T Keir; Raushan T Kurmasheva; Igor Dvorchik; Jianrong Wu; Catherine A Billups; Nana Boateng; Malcolm A Smith; Richard B Lock; Peter J Houghton
Journal: Cancer Res Date: 2016-08-05 Impact factor: 12.701

Review 3. Human tumor xenografts as model for drug testing.

Authors: J Mattern; M Bak; E W Hahn; M Volm
Journal: Cancer Metastasis Rev Date: 1988-11 Impact factor: 9.264

Review 4. Predictive tests in cancer chemotherapy. A reappraisal.

Authors: R Osieka; S Seeber; C G Schmidt
Journal: Klin Wochenschr Date: 1984-03-01

5. Induction of sarcomas in athymic mice.

Authors: G M Beattie; A F Knowles; F C Jensen; S M Baird; N O Kaplan
Journal: Proc Natl Acad Sci U S A Date: 1982-05 Impact factor: 11.205

6. In vivo induction of neoplastic growth in nude mouse connective tissue adjacent to xenografted human tumors.

Authors: H J Staab; H Heilbronner; M Schrader; F A Anderer
Journal: J Cancer Res Clin Oncol Date: 1983 Impact factor: 4.553

Review 7. Tumor progression in metastasis: an experimental approach using lectin resistant tumor variants.

Authors: R S Kerbel; J W Dennis; A E Largarde; P Frost
Journal: Cancer Metastasis Rev Date: 1982 Impact factor: 9.264

8. Evaluation of 9-dimethylaminomethyl-10-hydroxycamptothecin against xenografts derived from adult and childhood solid tumors.

Authors: P J Houghton; P J Cheshire; L Myers; C F Stewart; T W Synold; J A Houghton
Journal: Cancer Chemother Pharmacol Date: 1992 Impact factor: 3.333

9. Evaluation of a novel bis-naphthalimide anticancer agent, DMP 840, against human xenografts derived from adult, juvenile, and pediatric cancers.

Authors: P J Houghton; P J Cheshire; J C Hallman; J L Gross; R J McRipley; J H Sun; C H Behrens; D L Dexter; J A Houghton
Journal: Cancer Chemother Pharmacol Date: 1994 Impact factor: 3.333

10. Evaluation of 3-(p-fluorophenyl)-L-alanyl-3-[m-bis-(2-chloroethyl) aminophenyl]-L-alanyl-L-methionine ethyl ester HCl (PTT.119) against xenografts of human rhabdomyosarcoma.

Authors: P J Houghton; R Tharp; J A Houghton; J F Holland; J G Bekesi
Journal: Cancer Chemother Pharmacol Date: 1988 Impact factor: 3.333