Literature DB >> 6294141

Preferential binding of vasoactive intestinal polypeptide to basolateral membrane of rat and rabbit enterocytes.

K Dharmsathaphorn, V Harms, D J Yamashiro, R J Hughes, H J Binder, E M Wright.   

Abstract

Binding of radioiodinated vasoactive intestinal polypeptide (VIP) to intestinal cell membranes of the rabbit ileum and rat jejunum was investigated. Specific binding of 125I-labeled VIP could be demonstrated only on the basolateral membrane and not on the brush border membrane. This corresponded with the lack of an effect on ion transport when VIP was applied to the mucosal side of an in vitro preparation of rabbit ileum. VIP altered ion transport only when it was applied to the serosal side. The binding of 125I-VIP was specific and dependent upon incubation temperature. There was a close correlation between the potency of VIP for inhibition of 125I-VIP binding and that for increasing adenylate cyclase activity. These observations demonstrate that VIP receptors are located on the basolateral membrane.

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Year:  1983        PMID： 6294141      PMCID： PMC436834          DOI： 10.1172/jci110748

Source DB:  PubMed          Journal:  J Clin Invest        ISSN： 0021-9738            Impact factor:   14.808


  29 in total

1.  Alteration of large intestinal electrolyte transport by vasoactive intestinal polypeptide in the rat.

Authors:  L C Racusen; H J Binder
Journal:  Gastroenterology       Date:  1977-10       Impact factor: 22.682

Review 2.  Adenylate cyclase assay.

Authors:  Y Salomon
Journal:  Adv Cyclic Nucleotide Res       Date:  1979

3.  Interaction of porcine vasoactive intestinal peptide with dispersed pancreatic acinar cells from the guinea pig. Binding of radioiodinated peptide.

Authors:  J P Christophe; T P Conlon; J D Gardner
Journal:  J Biol Chem       Date:  1976-08-10       Impact factor: 5.157

4.  Effects of vasoactive intestinal peptide, secretin, and related peptides on rat colonic transport and adenylate cyclase activity.

Authors:  D B Waldman; J D Gardner; A M Zfass; G M Makhlouf
Journal:  Gastroenterology       Date:  1977-09       Impact factor: 22.682

5.  Vasoactive intestinal polypeptide: specific binding to rat brain membranes.

Authors:  D P Taylor; C B Pert
Journal:  Proc Natl Acad Sci U S A       Date:  1979-02       Impact factor: 11.205

6.  Localization of the action of cholera toxin on adenyl cyclase in mucosal epithelial cells of rabbit intestine.

Authors:  D K Parkinson; H Ebel; D R DiBona; G W Sharp
Journal:  J Clin Invest       Date:  1972-09       Impact factor: 14.808

7.  Potassium activated phosphatase from human red blood cells. The mechanism of potassium activation.

Authors:  P J Garrahan; M I Pouchan; A F Rega
Journal:  J Physiol       Date:  1969-06       Impact factor: 5.182

8.  Neurohumoral control of ileal electrolyte transport. I. Bombesin and related peptides.

Authors:  J F Kachur; R J Miller; M Field; J Rivier
Journal:  J Pharmacol Exp Ther       Date:  1982-03       Impact factor: 4.030

9.  In vitro effects of somatostatin on ion transport in rabbit intestine.

Authors:  S Guandalini; J F Kachur; P L Smith; R J Miller; M Field
Journal:  Am J Physiol       Date:  1980-02

10.  Insulin binding and degradation by luminal and basolateral tubular membranes from rabbit kidney.

Authors:  Z Talor; D S Emmanouel; A I Katz
Journal:  J Clin Invest       Date:  1982-05       Impact factor: 14.808
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  19 in total

1.  Simultaneous immunohistochemical demonstration of vasoactive intestinal polypeptide and its receptor in human colon.

Authors:  W Kummer
Journal:  Histochem J       Date:  1990-05

2.  Fluid absorption in isolated perfused colonic crypts.

Authors:  S K Singh; H J Binder; W F Boron; J P Geibel
Journal:  J Clin Invest       Date:  1995-11       Impact factor: 14.808

3.  Vasoactive intestinal peptide stimulation of human renal adenylate cyclase in vitro.

Authors:  B G Charlton; D E Neal; N L Simmons
Journal:  J Physiol       Date:  1990-04       Impact factor: 5.182

4.  Vasoactive intestinal polypeptide-induced chloride secretion by a colonic epithelial cell line. Direct participation of a basolaterally localized Na+,K+,Cl- cotransport system.

Authors:  K Dharmsathaphorn; K G Mandel; H Masui; J A McRoberts
Journal:  J Clin Invest       Date:  1985-02       Impact factor: 14.808

5.  Distribution of vasoactive intestinal peptide-sensitive adenylate cyclase activity along the rabbit nephron.

Authors:  N M Griffiths; D Chabardès; M Imbert-Teboul; S Siaume-Perez; F Morel; N L Simmons
Journal:  Pflugers Arch       Date:  1988-09       Impact factor: 3.657

Review 6.  Vasoactive intestinal peptide.

Authors:  S I Said
Journal:  J Endocrinol Invest       Date:  1986-04       Impact factor: 4.256

7.  Effect of vasoactive intestinal polypeptide on the release of serotonin from the in vitro vascularly perfused small intestine of guinea pig.

Authors:  H Schwörer; K Racké; H Kilbinger
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1989-05       Impact factor: 3.000

8.  Vasoactive intestinal polypeptide regulation of rabbit renal adenylate cyclase activity in vitro.

Authors:  N M Griffiths; N L Simmons
Journal:  J Physiol       Date:  1987-06       Impact factor: 5.182

9.  Vasoactive intestinal peptide stimulation of renal adenylate cyclase and antagonism by (4Cl-D-Phe6Leu17)VIP.

Authors:  N M Griffiths; N L Simmons; J Rivier
Journal:  Pflugers Arch       Date:  1989-06       Impact factor: 3.657

10.  HCl-stimulated duodenal HCO3- secretion in conscious rat. Interactions among VIP, nicotinic receptor mechanisms, and prostaglandins.

Authors:  B Smedfors; E Theodorsson; C Johansson
Journal:  Dig Dis Sci       Date:  1994-10       Impact factor: 3.199
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