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Literature DB >> 6291866

Simultaneous simulation of the serum profiles of two antibiotics and analysis of the combined effect against a culture of Pseudomonas aeruginosa.

A Bauernfeind, R Jungwirth, C Petermüller.

Abstract

The serum profiles of ceftriaxone (CEF) and netilmicin (NET) were produced in a liquid culture of Pseudomonas aeruginosa, and the change in viable count recorded. Synergism was detectable between CEF and NET despite of the widely disparate serum halflife times of NET and CEF.

Entities: Chemical Species

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Year: 1982 PMID： 6291866 DOI： 10.1159/000238100

Source DB: PubMed Journal: Chemotherapy ISSN： 0009-3157 Impact factor: 2.544

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Cited

9 in total

1. [Antibacterial activity and beta-lactamase stability of eleven oral cephalosporins].

Authors: A Bauernfeind; R Jungwirth; S Schweighart; M Theopold
Journal: Infection Date: 1990 Impact factor: 3.553

2. [Dependence of the bactericidal activity and mutant selection of 4-quinolones on their serum concentration levels].

Authors: A Bauernfeind; C Petermüller; B Heinrich; R Gablac
Journal: Infection Date: 1986 Impact factor: 3.553

3. Selection of antibiotics for treatment and prophylaxis of staphylococcal infections in cystic fibrosis patients.

Authors: A Bauernfeind; B Przyklenk; C Matthias; R Jungwirth; R M Bertele; K Harms
Journal: Infection Date: 1990 Mar-Apr Impact factor: 3.553

4. Killing of Pseudomonas aeruginosa during continuous and intermittent infusion of ceftazidime in an in vitro pharmacokinetic model.

Authors: J W Mouton; J G den Hollander
Journal: Antimicrob Agents Chemother Date: 1994-05 Impact factor: 5.191

5. Perspectives of beta-lactamases inhibitors in therapy of infections caused by Escherichia coli or Klebsiella with plasmidic resistance to third generation cephalosporins.

Authors: A Bauernfeind
Journal: Infection Date: 1990 Jan-Feb Impact factor: 3.553

Simultaneous simulation of the serum profiles of two antibiotics and analysis of the combined effect against a culture of Pseudomonas aeruginosa.

1. [Antibacterial activity and beta-lactamase stability of eleven oral cephalosporins].

2. [Dependence of the bactericidal activity and mutant selection of 4-quinolones on their serum concentration levels].

3. Selection of antibiotics for treatment and prophylaxis of staphylococcal infections in cystic fibrosis patients.

4. Killing of Pseudomonas aeruginosa during continuous and intermittent infusion of ceftazidime in an in vitro pharmacokinetic model.

5. Perspectives of beta-lactamases inhibitors in therapy of infections caused by Escherichia coli or Klebsiella with plasmidic resistance to third generation cephalosporins.

Review 6. Ceftriaxone. A review of its antibacterial activity, pharmacological properties and therapeutic use.

7. Bacteriostatic and bactericidal activity of penicillins at constant and variable concentrations.

8. Comparative pharmacodynamics of clarithromycin and azithromycin against respiratory pathogens.

9. In vitro and in vivo synergy between ceftriaxone and aminoglycosides against Pseudomonas aeruginosa.