Literature DB >> 3082765

[Dependence of the bactericidal activity and mutant selection of 4-quinolones on their serum concentration levels].

A Bauernfeind, C Petermüller, B Heinrich, R Gablac.   

Abstract

In an in vitro system, bacterial cultures were exposed to concentrations following the kinetics of 4-quinolones in human serum. Both killing kinetics of staphylococci and enterococci and selection of resistant mutants were shown to be influenced by the pharmacokinetik parameters of the individual substances.

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Year:  1986        PMID： 3082765     DOI： 10.1007/bf01645194

Source DB:  PubMed          Journal:  Infection        ISSN： 0300-8126            Impact factor:   3.553


  7 in total

1.  Pharmacokinetics and tissue penetration of ciprofloxacin.

Authors:  B Crump; R Wise; J Dent
Journal:  Antimicrob Agents Chemother       Date:  1983-11       Impact factor: 5.191

2.  In-vitro activity of enoxacin, ofloxacin, norfloxacin and nalidixic acid.

Authors:  A Bauernfeind; U Ullmann
Journal:  J Antimicrob Chemother       Date:  1984-09       Impact factor: 5.790

3.  Simultaneous simulation of the serum profiles of two antibiotics and analysis of the combined effect against a culture of Pseudomonas aeruginosa.

Authors:  A Bauernfeind; R Jungwirth; C Petermüller
Journal:  Chemotherapy       Date:  1982       Impact factor: 2.544

4.  Antibacterial activities of ciprofloxacin, norfloxacin, oxolinic acid, cinoxacin, and nalidixic acid.

Authors:  A L Barry; R N Jones; C Thornsberry; L W Ayers; E H Gerlach; H M Sommers
Journal:  Antimicrob Agents Chemother       Date:  1984-05       Impact factor: 5.191

Review 5.  Norfloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Authors:  B Holmes; R N Brogden; D M Richards
Journal:  Drugs       Date:  1985-12       Impact factor: 9.546

6.  Absorption, distribution, metabolic fate, and elimination of pefloxacin mesylate in mice, rats, dogs, monkeys, and humans.

Authors:  G Montay; Y Goueffon; F Roquet
Journal:  Antimicrob Agents Chemother       Date:  1984-04       Impact factor: 5.191

7.  In vitro activity of ciprofloxacin, norfloxacin and nalidixic acid.

Authors:  A Bauernfeind; C Petermüller
Journal:  Eur J Clin Microbiol       Date:  1983-04       Impact factor: 3.267
  7 in total
  4 in total

Review 1.  In vitro antibacterial activity and pharmacodynamics of new quinolones.

Authors:  A Dalhoff; F-J Schmitz
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2003-04-01       Impact factor: 3.267

2.  Twenty-four-hour area under the concentration-time curve/MIC ratio as a generic predictor of fluoroquinolone antimicrobial effect by using three strains of Pseudomonas aeruginosa and an in vitro pharmacodynamic model.

Authors:  K J Madaras-Kelly; B E Ostergaard; L B Hovde; J C Rotschafer
Journal:  Antimicrob Agents Chemother       Date:  1996-03       Impact factor: 5.191

3.  Ciprofloxacin and norfloxacin for selective decontamination in patients with severe granulocytopenia.

Authors:  G Maschmeyer; E Haralambie; W Gaus; W Kern; A W Dekker; H G De Vries-Hospers; W Sizoo; W König; F Gutzler; S Daenen
Journal:  Infection       Date:  1988 Mar-Apr       Impact factor: 3.553

4.  [A cross-over study on the effectiveness of ofloxacin and ciprofloxacin administered orally].

Authors:  C C Kurz; W Marget; K Harms; R M Bertele
Journal:  Infection       Date:  1986       Impact factor: 3.553
  4 in total

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