| Literature DB >> 6291673 |
A W Schwartz, H Joosten, A B Voet.
Abstract
Adenine is produced (after hydrolysis) when 0.01 M solutions of HCN are adjusted to pH 9.2 with NH4OH and are frozen at -2 degrees C for 60-100 days. The addition of glycolonitrile (the cyanohydrin of formaldehyde) increases the yield of adenine under these conditions by about five-fold. These results confirm and extend an earlier suggestion that purine synthesis on the prebiotic Earth might have occurred in frozen, dilute solutions of HCN.Entities:
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Year: 1982 PMID： 6291673 DOI： 10.1016/0303-2647(82)90003-x
Source DB: PubMed Journal: Biosystems ISSN： 0303-2647 Impact factor: 1.973