Literature DB >> 6286920

Inhibition of calmodulin by phenothiazines and related drugs: structure-activity relationships.

W C Prozialeck, B Weiss.   

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Year:  1982        PMID: 6286920

Source DB:  PubMed          Journal:  J Pharmacol Exp Ther        ISSN: 0022-3565            Impact factor:   4.030


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  53 in total

1.  Reversal of drug resistance in sarcoma-45 by the new calmodulin antagonist--trihydrochloride of [1,2,5-trimethyl-4-phenyl-4-beta-[N-(beta-ethylamino)-N-4'-methoxybe nzy l]-ethylamino] piperidine (AR-2).

Authors:  A R Alexanian; N S Arutyunian
Journal:  Invest New Drugs       Date:  1999       Impact factor: 3.850

2.  Disruption of mitochondrial function as the basis of the trypanocidal effect of trifluoperazine on Trypanosoma cruzi.

Authors:  J L Lacuara; S R de Barioglio; P P de Oliva; A S Bernacchi; A F de Culasso; J A Castro; B M Franke de Cazzulo; J J Cazzulo
Journal:  Experientia       Date:  1991-06-15

3.  Tracheary-element differentiation in suspension-cultured cells ofZinnia requires uptake of extracellular Ca(2+) : Experiments with calcium-channel blockers and calmodulin inhibitors.

Authors:  A W Roberts; C H Haigler
Journal:  Planta       Date:  1990-03       Impact factor: 4.116

4.  Correlates of aldosterone-induced increases in Cai2+ and Isc suggest that Cai2+ is the second messenger for stimulation of apical membrane conductance.

Authors:  D Petzel; M B Ganz; E J Nestler; J J Lewis; J Goldenring; F Akcicek; J P Hayslett
Journal:  J Clin Invest       Date:  1992-01       Impact factor: 14.808

5.  Antidepressant-induced ubiquitination and degradation of the cardiac potassium channel hERG.

Authors:  Adrienne T Dennis; Drew Nassal; Isabelle Deschenes; Dierk Thomas; Eckhard Ficker
Journal:  J Biol Chem       Date:  2011-08-09       Impact factor: 5.157

6.  A molecular modeling study on binding of drugs to calmodulin.

Authors:  H D Höltje; M Hense
Journal:  J Comput Aided Mol Des       Date:  1989-06       Impact factor: 3.686

7.  Neuroleptic drugs attenuate calcium influx and tension development in rabbit thoracic aorta: effects of pimozide, penfluridol, chlorpromazine, and haloperidol.

Authors:  S F Flaim; M D Brannan; S C Swigart; M M Gleason; L D Muschek
Journal:  Proc Natl Acad Sci U S A       Date:  1985-02       Impact factor: 11.205

8.  Properties of a microtubule-associated cofactor-independent protein kinase from pig brain.

Authors:  C W Scott; C B Caputo; A I Salama
Journal:  Biochem J       Date:  1989-10-01       Impact factor: 3.857

9.  A repurposing approach identifies off-patent drugs with fungicidal cryptococcal activity, a common structural chemotype, and pharmacological properties relevant to the treatment of cryptococcosis.

Authors:  Arielle Butts; Louis DiDone; Kristy Koselny; Bonnie K Baxter; Yeissa Chabrier-Rosello; Melanie Wellington; Damian J Krysan
Journal:  Eukaryot Cell       Date:  2012-12-14

10.  Bepridil and cetiedil. Vasodilators which inhibit Ca2+-dependent calmodulin interactions with erythrocyte membranes.

Authors:  P Agre; D Virshup; V Bennett
Journal:  J Clin Invest       Date:  1984-09       Impact factor: 14.808

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