Literature DB >> 6284788

The role of the human major histocompatibility complex in cytotoxic T-cell responses to virus-infected cells.

W E Biddison.   

Abstract

The human major histocompatibility complex (HLA) has been demonstrated to play two roles in the generation and expression of cytotoxic T-lymphocyte responses to virus-infected cells: (1) cytotoxic T cells can only recognize viral antigens in conjunction with antigens encoded by HLA-A and -B genes; and (2) HLA-linked genes may control the capacity to generate T-cell responses to a given virus or to virus in conjunction with particular self HLA-A and -B antigens. Analysis of T-cell responses generated in vivo to Epstein-Barr virus suggests that human T cells may recognize virus in conjunction with antigens other than the class I HLA polymorphic specificities.

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Year:  1982        PMID: 6284788     DOI: 10.1007/bf00915971

Source DB:  PubMed          Journal:  J Clin Immunol        ISSN: 0271-9142            Impact factor:   8.317


  49 in total

1.  Y-antigen killing by T cells of women is restricted by HLA.

Authors:  E Goulmy; A Termijtelen; B A Bradley; J J van Rood
Journal:  Nature       Date:  1977-04-07       Impact factor: 49.962

2.  Family studies define a new histocompatibility locus, SB, between HLA-DR and GLO.

Authors:  S Shaw; P Kavathas; M S Pollack; D Charmot; C Mawas
Journal:  Nature       Date:  1981-10-29       Impact factor: 49.962

3.  A biological role for the major histocompatibility antigens.

Authors:  P C Doherty; R M Zinkernagel
Journal:  Lancet       Date:  1975-06-28       Impact factor: 79.321

4.  Human cell-mediated cytotoxicity against modified target cells is restricted by HLA.

Authors:  E Dickmeiss; B Soeberg; A Svejgaard
Journal:  Nature       Date:  1977-12-08       Impact factor: 49.962

5.  Virus-immune cytotoxic T cells recognize structural differences between serologically indistinguishable HLA-A2 molecules.

Authors:  W E Biddison; M S Krangel; J L Strominger; F E Ward; G M Shearer; S Shaw
Journal:  Hum Immunol       Date:  1980-10       Impact factor: 2.850

6.  Capacity of sensitized thymus-derived lymphocytes to induce fatal lymphocytic choriomeningitis is restricted by the H-2 gene complex.

Authors:  P C Doherty; R M Zinernagel
Journal:  J Immunol       Date:  1975-01       Impact factor: 5.422

7.  The recovery of mice from influenza A virus infection: adoptive transfer of immunity with influenza virus-specific cytotoxic T lymphocytes recognizing a common virion antigen.

Authors:  K L Yap; G L Ada
Journal:  Scand J Immunol       Date:  1978       Impact factor: 3.487

8.  T cell subpopulations required for the human cytotoxic T lymphocyte response to influenza virus: evidence for T cell help.

Authors:  W E Biddison; S O Sharrow; G M Shearer
Journal:  J Immunol       Date:  1981-08       Impact factor: 5.422

9.  Evidence for a new segregant series of B cell antigens that are encoded in the HLA-D region and that stimulate secondary allogenic proliferative and cytotoxic responses.

Authors:  S Shaw; A H Johnson; G M Shearer
Journal:  J Exp Med       Date:  1980-09-01       Impact factor: 14.307

10.  HLA-linked genetic control of the specicity of human cytotoxic T-cell responses to influenza virus.

Authors:  S Shaw; W E Biddison
Journal:  J Exp Med       Date:  1979-03-01       Impact factor: 14.307

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  7 in total

1.  Pathogenic and protective correlates of T cell proliferation in AIDS. HNRC Group. HIV Neurobehavioral Research Center.

Authors:  R D Schrier; C A Wiley; C Spina; J A McCutchan; I Grant
Journal:  J Clin Invest       Date:  1996-08-01       Impact factor: 14.808

2.  Deficient autologous mixed lymphocyte reaction in Kaposi's sarcoma associated with deficiency of Leu-3+ responder T cells.

Authors:  S Gupta; B Safai
Journal:  J Clin Invest       Date:  1983-02       Impact factor: 14.808

3.  Autologous mixed lymphocyte reaction in man: XV. Cellular and molecular basis of deficient autologous mixed lymphocyte response in insulin-dependent diabetes mellitus.

Authors:  K G Chandy; A M Charles; A Kershnar; B Buckingham; N Waldeck; S Gupta
Journal:  J Clin Immunol       Date:  1984-11       Impact factor: 8.317

4.  Functional T lymphocyte immune deficiency in a population of homosexual men who do not exhibit symptoms of acquired immune deficiency syndrome.

Authors:  G M Shearer; S M Payne; L J Joseph; W E Biddison
Journal:  J Clin Invest       Date:  1984-08       Impact factor: 14.808

5.  Killing of measles virus-infected cells by human cytotoxic T cells.

Authors:  C J Lucas; W E Biddison; D L Nelson; S Shaw
Journal:  Infect Immun       Date:  1982-10       Impact factor: 3.441

6.  Interleukin-2 enhances the depressed natural killer and cytomegalovirus-specific cytotoxic activities of lymphocytes from patients with the acquired immune deficiency syndrome.

Authors:  A H Rook; H Masur; H C Lane; W Frederick; T Kasahara; A M Macher; J Y Djeu; J F Manischewitz; L Jackson; A S Fauci; G V Quinnan
Journal:  J Clin Invest       Date:  1983-07       Impact factor: 14.808

7.  Adult human glial cells can present target antigens to HLA-restricted cytotoxic T-cells.

Authors:  S Dhib-Jalbut; C V Kufta; M Flerlage; N Shimojo; H F McFarland
Journal:  J Neuroimmunol       Date:  1990 Sep-Oct       Impact factor: 3.478

  7 in total

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