Literature DB >> 49564

A biological role for the major histocompatibility antigens.

P C Doherty, R M Zinkernagel.   

Abstract

A central function of the major histo-compatibility (H) antigens may be to signal changes in self to the immune system. Virus-induced modification of strong transplantation antigens apparently results in recognition by thymus-derived lymphocytes (T cells), with subsequent clonal expansion and immune elimination of cells bearing non-self determinants. The extreme genetic polymorphism found in the major H antigen systems of higher vertebrates may reflect evolutionary pressure exerted by this immunological surveillance mechanism.

Mesh：

Substances：

Year:  1975        PMID： 49564     DOI： 10.1016/s0140-6736(75)92610-0

Source DB:  PubMed          Journal:  Lancet        ISSN： 0140-6736            Impact factor:   79.321


  118 in total

1.  The birth of clinical organ transplantation.

Authors:  T E Starzl
Journal:  J Am Coll Surg       Date:  2001-04       Impact factor: 6.113

Review 2.  Regulation of immune reactivity and tolerance by antigen migration and localization: with particular reference to allo- and xenotransplantation.

Authors:  T E Starzl; N Murase; A W Thomson; M Trucco; A Rao
Journal:  Transplant Proc       Date:  1999-06       Impact factor: 1.066

Review 3.  Immunity and tolerance are related, and governed by antigen migration and localization.

Authors:  T E Starzl; N Murase; A W Thomson; M Trucco; A Rao
Journal:  Transplant Proc       Date:  1999 Feb-Mar       Impact factor: 1.066

4.  History of clinical transplantation.

Authors:  T E Starzl
Journal:  World J Surg       Date:  2000-07       Impact factor: 3.352

5.  Major histocompatibility complex differentiation in Sacramento River chinook salmon.

Authors:  T J Kim; K M Parker; P W Hedrick
Journal:  Genetics       Date:  1999-03       Impact factor: 4.562

6.  The effects of thymic selection on the range of T cell cross-reactivity.

Authors:  Dennis L Chao; Miles P Davenport; Stephanie Forrest; Alan S Perelson
Journal:  Eur J Immunol       Date:  2005-12       Impact factor: 5.532

Review 7.  HLA and disease.

Authors:  Yogita Ghodke; Kalpana Joshi; Arvind Chopra; Bhushan Patwardhan
Journal:  Eur J Epidemiol       Date:  2005       Impact factor: 8.082

8.  The mystique of organ transplantation.

Authors:  Thomas E Starzl
Journal:  J Am Coll Surg       Date:  2005-08       Impact factor: 6.113

9.  Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy.

Authors:  Diego Chowell; Luc G T Morris; Claud M Grigg; Jeffrey K Weber; Robert M Samstein; Vladimir Makarov; Fengshen Kuo; Sviatoslav M Kendall; David Requena; Nadeem Riaz; Benjamin Greenbaum; James Carroll; Edward Garon; David M Hyman; Ahmet Zehir; David Solit; Michael Berger; Ruhong Zhou; Naiyer A Rizvi; Timothy A Chan
Journal:  Science       Date:  2017-12-07       Impact factor: 47.728

10.  HLA-DPB1 and anti-HBs titer kinetics in hepatitis B booster recipients who completed primary hepatitis B vaccination during infancy.

Authors:  T-W Wu; C-C Chu; H-W Chang Liao; S-K Lin; T-Y Ho; M Lin; H H Lin; L-Y Wang
Journal:  Genes Immun       Date:  2013-11-28       Impact factor: 2.676
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.