Literature DB >> 6284377

Stage-specific transforming genes of human and mouse B- and T-lymphocyte neoplasms.

M A Lane, A Sainten, G M Cooper.   

Abstract

DNAs of 20 B- and T-lymphocyte neoplasms of human and mouse origin induced transformation of NIH/3T3 cells with high efficiencies, indicating that these neoplasms contained activated transforming genes that were detectable by transfection. Analysis of the susceptibility of the transforming activities of lymphocyte-neoplasm DNAs to digestion with restriction endonucleases indicated that the same or closely related transforming genes were activated in independent neoplasms representative of the same stage of normal cell differentiation. However, different transforming genes were activated in neoplasms representative of different stages of normal B- and T-lymphocyte differentiation. These results indicate that specific transforming genes are activated in neoplasms of discrete stages of differentiation within these cell lineages.

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Year:  1982        PMID： 6284377     DOI： 10.1016/0092-8674(82)90066-6

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  39 in total

1.  RhoGTPases and p53 are involved in the morphological appearance and interferon-alpha response of hairy cells.

Authors:  Benjamin Chaigne-Delalande; Lynda Deuve; Edith Reuzeau; Caroline Basoni; David Lafarge; Christine Varon; Florence Tatin; Guerric Anies; Richard Garand; Ijsbrand Kramer; Elisabeth Génot
Journal:  Am J Pathol       Date:  2006-02       Impact factor: 4.307

2.  Genomic sequence of the mouse oncogene tlm.

Authors:  M A Lane; M B Tobin
Journal:  Nucleic Acids Res       Date:  1990-06-11       Impact factor: 16.971

3.  Expression of human CD antigens, including CD1 and CD25, by human x mouse interlineage leukaemia hybrids.

Authors:  G M Taylor; H Morten; T Carr; C Harrison; J Ridway; P Morris Jones
Journal:  Immunology       Date:  1987-12       Impact factor: 7.397

Review 4.  Somatic cell fusion as a source of genetic rearrangement leading to metastatic variants.

Authors:  L Larizza; V Schirrmacher
Journal:  Cancer Metastasis Rev       Date:  1984       Impact factor: 9.264

Review 5.  Human oncogenes.

Authors:  K Willecke; R Schäfer
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

6.  Isolation and characterization of a stage-specific transforming gene, Tlym-I, from T-cell lymphomas.

Authors:  M A Lane; A Sainten; K M Doherty; G M Cooper
Journal:  Proc Natl Acad Sci U S A       Date:  1984-04       Impact factor: 11.205

7.  Regional chromosomal localization of N-ras, K-ras-1, K-ras-2 and myb oncogenes in human cells.

Authors:  O W McBride; D C Swan; S R Tronick; R Gol; D Klimanis; D E Moore; S A Aaronson
Journal:  Nucleic Acids Res       Date:  1983-12-10       Impact factor: 16.971

8.  A position 12-activated H-ras oncogene in all HS578T mammary carcinosarcoma cells but not normal mammary cells of the same patient.

Authors:  M H Kraus; Y Yuasa; S A Aaronson
Journal:  Proc Natl Acad Sci U S A       Date:  1984-09       Impact factor: 11.205

Review 9.  Karyotypic progression in human tumors.

Authors:  S R Wolman
Journal:  Cancer Metastasis Rev       Date:  1983       Impact factor: 9.264

10.  Identification of an antigen associated with transforming genes of human and mouse mammary carcinomas.

Authors:  D Becker; M A Lane; G M Cooper
Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205
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