Literature DB >> 6280466

Local control of inflammatory pain.

S H Ferreira.   

Abstract

The mechanism of the local hyperalgesic action of prostaglandin E2 has been studied using rat paw oedema. Prostaglandin E2 is a metabotropic transmitter, activating adenylate cyclase, either directly or through the release of a stimulatory protein factor. This activation of adenylate-cyclase is blocked, locally, by opiates. Hyperalgesia results from the alteration of the cAMP/Ca2+ balance after chemical or mechanical initiation of generator potentials at the nociceptor.

Entities:  

Mesh：

Substances：

Year:  1981        PMID： 6280466     DOI： 10.1007/bf01978773

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  10 in total

1.  Inhibition of prostaglandin biosynthesis as the mechanism of analgesia of aspirin-like drugs in the dog knee joint.

Authors:  S Moncada; S H Ferreira; J R Vane
Journal:  Eur J Pharmacol       Date:  1975-04       Impact factor: 4.432

2.  Prostaglandins, aspirin-like drugs and analgesia.

Authors:  S H Ferreira
Journal:  Nat New Biol       Date:  1972-12-13

3.  Nociceptive response to prostaglandins and analgesic actions of aspirin and morphine.

Authors:  H O Collier; C Schneider
Journal:  Nat New Biol       Date:  1972-04-05

4.  II - Prostaglandin hyperalgesia: the peripheral analgesic activity of morphine, enkephalins and opioid antagonists.

Authors:  S H Ferreira; M Nakamura
Journal:  Prostaglandins       Date:  1979-08

5.  I - Prostaglandin hyperalgesia, a cAMP/Ca2+ dependent process.

Authors:  S H Ferreira; M Nakamura
Journal:  Prostaglandins       Date:  1979-08

6.  Prostaglandin E1 raises the cAMP content of peripheral nerve tissue.

Authors:  P Kalix
Journal:  Neurosci Lett       Date:  1979-05       Impact factor: 3.046

7.  Central and peripheral antialgesic action of aspirin-like drugs.

Authors:  S H Ferreira; B B Lorenzetti; F M Corrêa
Journal:  Eur J Pharmacol       Date:  1978-12-15       Impact factor: 4.432

8.  The hyperalgesic effects of prostacyclin and prostaglandin E2.

Authors:  S H Ferreira; M Nakamura; M S de Abreu Castro
Journal:  Prostaglandins       Date:  1978-07

9.  Prostaglandins and the mechanism of analgesia produced by aspirin-like drugs.

Authors:  S H Ferreira; S Moncada; J R Vane
Journal:  Br J Pharmacol       Date:  1973-09       Impact factor: 8.739

10.  III - Prostaglandin hyperalgesia: relevance of the peripheral effect for the analgesic action of opioid-antagonists.

Authors:  S H Ferreira; M Nakamura
Journal:  Prostaglandins       Date:  1979-08
  10 in total
  4 in total

1.  Protective effects of indomethacin and cyclophosphamide but not of infliximab on liver metabolic changes caused by adjuvant-induced arthritis.

Authors:  Maria Angélica Raffaini Covas Pereira da Silva; Ciomar Aparecida Bersani-Amado; Emy Luiza Ishii-Iwamoto; Lívia Bracht; Silvana Martins Caparroz-Assef
Journal:  Inflammation       Date:  2011-12       Impact factor: 4.092

2.  Pain management for dentists: the role of ibuprofen.

Authors:  Alessandro Pozzi; Luca Gallelli
Journal:  Ann Stomatol (Roma)       Date:  2012-04-15

Review 3.  Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.

Authors:  William G Robichaux; Xiaodong Cheng
Journal:  Physiol Rev       Date:  2018-04-01       Impact factor: 37.312

4.  A double-blind, placebo controlled, cross-over comparison of the analgesic effect of ibuprofen 400 mg and 800 mg on laser-induced pain.

Authors:  J C Nielsen; P Bjerring; L Arendt-Nielsen; K J Petterson
Journal:  Br J Clin Pharmacol       Date:  1990-11       Impact factor: 4.335
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.