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Literature DB >> 6264273

Effect of DNA gyrase inhibitors on gene expression of the cysteine regulon.

Abstract

Nalidixic acid inhibits the expression of those cysteine genes which are regulated by the cysB product, it has no affect, however, on the constitutively-expressed cysE gene. The expression of cysteine genes in a strain carrying a mutation in the nalA locus is resistant to this drug. Novobiocin affects the expression of cysteine genes similarly to nalidixic acid. The effect of nalidixic acid on the expression of genes in a cysteine constitutive mutant was studied.

Entities: Chemical

Mesh：

Substances：

Year: 1981 PMID： 6264273 DOI： 10.1007/bf00425612

Source DB: PubMed Journal: Mol Gen Genet ISSN： 0026-8925

19 in total

1. DNA gyrase and DNA supercoiling.

Authors: M Gellert; K Mizuuchi; M H O'Dea; H Ohmori; J Tomizawa
Journal: Cold Spring Harb Symp Quant Biol Date: 1979

2. Structure and activities of Escherichia coli DNA gyrase.

Authors: C L Peebles; N P Higgins; K N Kreuzer; A Morrison; P O Brown; A Sugino; N R Cozzarelli
Journal: Cold Spring Harb Symp Quant Biol Date: 1979

3. Determination of serum proteins by means of the biuret reaction.

Authors: A G GORNALL; C J BARDAWILL; M M DAVID
Journal: J Biol Chem Date: 1949-02 Impact factor: 5.157

4. Promoter-specific inhibition of transcription by antibiotics which act on DNA gyrase.

Authors: C L Smith; M Kubo; F Imamoto
Journal: Nature Date: 1978-10-05 Impact factor: 49.962

5. Mechanism of transcription of bacteriophage S13. II. Inhibition of phage-specific transcription by nalidixic acid.

Authors: A Puga; I Tessman
Journal: J Mol Biol Date: 1973-03-25 Impact factor: 5.469

6. Animal DNA-dependent RNA polymerases. Analysis of the RNAs synthesized on Simian virus 40 superhelical DNA by mammalian RNA polymerases AI and B.

Authors: J L Mandel; P Chambon
Journal: Eur J Biochem Date: 1974-01-16

1. Coupling between DNA replication and cell division mediated by the FtsA protein in Escherichia coli: a pathway independent of the SOS response, the "TER" pathway.

Authors: A Tormo; A Dopazo; A G de la Campa; M Aldea; M Vicente
Journal: J Bacteriol Date: 1985-11 Impact factor: 3.490

7. The effect of gyrase inhibitors and cyclic AMP on induction and glucose repression of the 6-hydroxy-nicotine oxidases in Arthrobacter oxidans.

Authors: R Brandsch; K Decker
Journal: Arch Microbiol Date: 1982-12-03 Impact factor: 2.552

7 in total

Effect of DNA gyrase inhibitors on gene expression of the cysteine regulon.

1. DNA gyrase and DNA supercoiling.

2. Structure and activities of Escherichia coli DNA gyrase.

3. Determination of serum proteins by means of the biuret reaction.

4. Promoter-specific inhibition of transcription by antibiotics which act on DNA gyrase.

5. Mechanism of transcription of bacteriophage S13. II. Inhibition of phage-specific transcription by nalidixic acid.

6. Animal DNA-dependent RNA polymerases. Analysis of the RNAs synthesized on Simian virus 40 superhelical DNA by mammalian RNA polymerases AI and B.

7. Modulation of gene expression by drugs affecting deoxyribonucleic acid gyrase.

8. Novel template requirements of N4 virion RNA polymerase.

9. METABOLIC REGULATION OF ADENOSINE TRIPHOSPHATE SULFURYLASE IN YEAST.

10. Constitutive mutation of cysJIH operon in a cysB deletion strain of Salmonella typhimurium.

1. Coupling between DNA replication and cell division mediated by the FtsA protein in Escherichia coli: a pathway independent of the SOS response, the "TER" pathway.

Review 2. DNA supercoiling and environmental regulation of gene expression in pathogenic bacteria.

3. DNA supercoiling and suppression of the leu-500 promoter mutation.

Review 4. Biology of bacterial deoxyribonucleic acid topoisomerases.

Review 5. Linkage map of Salmonella typhimurium, Edition VI.

6. Physiology of the SOS response: kinetics of lexA and recA transcriptional activity following induction.

7. The effect of gyrase inhibitors and cyclic AMP on induction and glucose repression of the 6-hydroxy-nicotine oxidases in Arthrobacter oxidans.