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Literature DB >> 6264143

Encephalomyocarditis viral RNA can be translated under conditions of poliovirus-induced translation shutoff in vivo.

Abstract

Superinfection with poliovirus of HeLa cells already infected with encephalomyocarditis (EMC) virus does not inhibit translation of EMC viral mRNA, whereas residual host translation is completely inhibited. This result indicates that the cap recognition factors inactivated by poliovirus are not required for translation of EMC viral mRNA in vivo, in agreement with previous in vitro experiments. This raises the question of why EMC virus has evolved a capindependent translation mechanism.

Entities: Disease Species

Mesh：

Substances：

Year: 1981 PMID： 6264143 PMCID： PMC171208

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

20 in total

1. Untranslated vesicular stomatitis virus messenger RNA after poliovirus infection.

Authors: E Ehrenfeld; H Lund
Journal: Virology Date: 1977-07-15 Impact factor: 3.616

2. Inhibition of translation by poliovirus: inactivation of a specific initiation factor.

Authors: J K Rose; H Trachsel; K Leong; D Baltimore
Journal: Proc Natl Acad Sci U S A Date: 1978-06 Impact factor: 11.205

3. Competition between cellular and viral mRNAs in vitro is regulated by a messenger discriminatory initiation factor.

Authors: F Golini; S S Thach; C H Birge; B Safer; W C Merrick; R E Thach
Journal: Proc Natl Acad Sci U S A Date: 1976-09 Impact factor: 11.205

4. A cell-free model of the encephalomyocarditis virus-induced inhibition of host cell protein synthesis.

Authors: Y V Svitkin; V A Ginevskaya; T Y Ugarova; V I Agol
Journal: Virology Date: 1978-06-01 Impact factor: 3.616

5. Replication of mengovirus in HeLa cells preinfected with nonreplicating poliovirus.

Authors: W McCormick; S Penman
Journal: J Virol Date: 1968-09 Impact factor: 5.103

6. 5'-terminal structure of poliovirus polyribosomal RNA is pUp.

Authors: M J Hewlett; J K Rose; D Baltimore
Journal: Proc Natl Acad Sci U S A Date: 1976-02 Impact factor: 11.205

7. The 5' end of poliovirus mRNA is not capped with m7G(5')ppp(5')Np.

Authors: A Nomoto; Y F Lee; E Wimmer
Journal: Proc Natl Acad Sci U S A Date: 1976-02 Impact factor: 11.205

8. Cellular protein synthesis shutoff by mengovirus: translation of nonviral and viral mRNA's in extracts from uninfected and infected Ehrlich ascites tumor cells.

Authors: S L Abreu; J Lucas-Lenard
Journal: J Virol Date: 1976-04 Impact factor: 5.103