Literature DB >> 6259937

Viral susceptibility of skin fibroblasts from patients with Huntington disease.

C A Miller, S Rasheed.   

Abstract

Cultured skin fibroblasts from patients with Huntington disease (HD) and age-matched controls were tested for susceptibility to vesicular stomatitis virus (VSV) and transformation by Kirsten mouse sarcoma virus (KiMSV). The HD and control cells could not be distinguished on the basis of viral replication, plaque morphology, virus yield, or susceptibility to transformation by KiMSV. These findings suggest that the HD gene product, if expressed within peripheral tissue, does not selectively alter or interfere with viral replication.

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Year:  1981        PMID： 6259937      PMCID： PMC1684962     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  18 in total

1.  Viral probes of aging in the human diploid cell strain WI-38.

Authors:  G A Tomkins; E J Stanbridge; L Hayflick
Journal:  Proc Soc Exp Biol Med       Date:  1974-06

2.  Analysis of virus replication in ageing human fibroblast cultures.

Authors:  J J Holland; D Kohne; M V Doyle
Journal:  Nature       Date:  1973-10-12       Impact factor: 49.962

3.  Differences in susceptibility of human cells to mouse sarcoma virus.

Authors:  V Klement; M H Freedman; R M McAllister; W A Nelson-Rees; R J Heubner
Journal:  J Natl Cancer Inst       Date:  1971-07       Impact factor: 13.506

4.  Transformation and virus growth by murine sarcoma viruses in human cells.

Authors:  S A Aaronson; G J Todaro
Journal:  Nature       Date:  1970-01-31       Impact factor: 49.962

5.  A useful quantitative semimicromethod for viral plaque assay.

Authors:  B Rager-Zisman; T C Merigan
Journal:  Proc Soc Exp Biol Med       Date:  1973-04

6.  Increased frequency of diabetes mellitus in patients with Huntington's chorea.

Authors:  S Podolsky; N A Leopold; D S Sax
Journal:  Lancet       Date:  1972-06-24       Impact factor: 79.321

7.  Fibroblast cultures in Huntington's disease.

Authors:  J H Menkes; N Stein
Journal:  N Engl J Med       Date:  1973-04-19       Impact factor: 91.245

8.  Increased susceptibility of Down's syndrome fibroblasts to transformation by SV40.

Authors:  G J Todaro; G M Martin
Journal:  Proc Soc Exp Biol Med       Date:  1967-04

9.  Susceptibility of human diploid fibroblast strains to transformation by SV40 virus.

Authors:  G J Todaro; H Green; M R Swift
Journal:  Science       Date:  1966-09-09       Impact factor: 47.728

10.  Human chromosome 21 dosage: effect on the expression of the interferon induced antiviral state.

Authors:  Y H Tan; E L Schneider; J Tischfield; C J Epstein; F H Ruddle
Journal:  Science       Date:  1974-10-04       Impact factor: 47.728
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  3 in total

Review 1.  The current state of research with peripheral tissues in Huntington disease.

Authors:  G C Beverstock
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

2.  The ups and downs of Huntington disease research.

Authors:  D E Comings
Journal:  Am J Hum Genet       Date:  1981-03       Impact factor: 11.025

3.  Inherited susceptibility to retrovirus-induced transformation of Gardner syndrome cells.

Authors:  S Rasheed; J S Rhim; E J Gardner
Journal:  Am J Hum Genet       Date:  1983-09       Impact factor: 11.025
  3 in total

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