Literature DB >> 4371269

Human chromosome 21 dosage: effect on the expression of the interferon induced antiviral state.

Y H Tan, E L Schneider, J Tischfield, C J Epstein, F H Ruddle.   

Abstract

Human primary skin fibroblasts trisomic for chromosome 13, 18, or 21 and diploid human skin fibroblasts were induced for an antiviral response with human interferon. The cells that were trisomnic for chromosome 21 were three to seven times more sensitive to protection by human interferon than the normal diploid or trisomic 18 or 13 fibroblasts. The differential response in trisomnic 21 cells is consistent with the known assignment of the human antiviral gene to chromosome 21.

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Year:  1974        PMID： 4371269     DOI： 10.1126/science.186.4158.61

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  45 in total

1.  Evidence for the lack of feedback regulation of gene activity and for the absence of subunit exchange between lactate dehydrogenase tetramers in vivo.

Authors:  B Nadal-Ginard
Journal:  Proc Natl Acad Sci U S A       Date:  1976-10       Impact factor: 11.205

2.  Somatic cell mapping of the bovine interferon-alpha receptor.

Authors:  J A Langer; R Puvanakrishnan; J E Womack
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

3.  Chromosomal localization of human genes governing the interferon-induced antiviral state.

Authors:  C Chany; M Vignal; P Couillin; N Van Cong; J Boué; A Boué
Journal:  Proc Natl Acad Sci U S A       Date:  1975-08       Impact factor: 11.205

Review 4.  Antiviral activity of interferons.

Authors:  R M Friedman
Journal:  Bacteriol Rev       Date:  1977-09

5.  Presence of human chromosome 21 alone is sufficient for hybrid cell sensitivity to human interferon.

Authors:  D L Slate; L Shulman; J B Lawrence; M Revel; F H Ruddle
Journal:  J Virol       Date:  1978-01       Impact factor: 5.103

6.  Genetic mapping of the Mx influenza virus resistance gene within the region of mouse chromosome 16 that is homologous to human chromosome 21.

Authors:  R H Reeves; B F O'Hara; W J Pavan; J D Gearhart; O Haller
Journal:  J Virol       Date:  1988-11       Impact factor: 5.103

7.  Interferon induction by vesicular stomatitis virus and its role in virus replication.

Authors:  J Vilcek; S Yamazaki; E A Havell
Journal:  Infect Immun       Date:  1977-12       Impact factor: 3.441

8.  Synteny between glycinamide ribonucleotide synthetase and superoxide dismutase (soluble).

Authors:  E E Moore; C Jones; F T Kao; D C Oates
Journal:  Am J Hum Genet       Date:  1977-07       Impact factor: 11.025

Review 9.  Down syndrome and the complexity of genome dosage imbalance.

Authors:  Stylianos E Antonarakis
Journal:  Nat Rev Genet       Date:  2016-12-28       Impact factor: 53.242

10.  Genetic analysis of the human cell surface: antigenic marker for the human X chromosome in human-mouse hybrids.

Authors:  B P Dorman; N Shimizu; F H Ruddle
Journal:  Proc Natl Acad Sci U S A       Date:  1978-05       Impact factor: 11.205
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