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Literature DB >> 6255102

Eaton-Lambert syndrome: a clinical and electrophysiological study of a patient treated with 4-aminopyridine.

D B Sanders, Y I Kim, J F Howard, C A Goetsch.

Abstract

In a patient with the Eaton-Lambert syndrome, 4-aminopyridine produced temporary improvement of clinical and electromyographic abnormalities. Application of the drug in vitro to intercostal muscle from the patient produced an increase in the evoked release of neurotransmitter from intramuscular nerves.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1980 PMID： 6255102 PMCID： PMC490748 DOI： 10.1136/jnnp.43.11.978

Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN： 0022-3050 Impact factor: 10.154

28 in total

1. A study of some electrophysiological properties of human intercostal muscle.

Authors: D ELMQVIST; T R JOHNS; S THESLEFF
Journal: J Physiol Date: 1960-12 Impact factor: 5.182

2. Electromyography and electric stimulation of nerves in diseases of motor unit; observations on myasthenic syndrome associated with malignant tumors.

Authors: L M EATON; E H LAMBERT
Journal: J Am Med Assoc Date: 1957-03-30

3. An electrophysiological and morphological study of the neuromuscular junction in patients with myasthenia gravis.

Authors: E X Albuquerque; J E Rash; R F Mayer; J R Satterfield
Journal: Exp Neurol Date: 1976-06 Impact factor: 5.330

4. A neuromuscular transmission block produced by a cancer tissue extract derived from a patient with the myasthenic syndrome.

Authors: K Ishikawa; J K Engelhardt; T Fujisawa; T Okamoto; H Katsuki
Journal: Neurology Date: 1977-02 Impact factor: 9.910

5. 4-aminopyridine--a new drug tested in the treatment of Eaton-Lambert syndrome.

Authors: H Lundh; O Nilsson; I Rosén
Journal: J Neurol Neurosurg Psychiatry Date: 1977-11 Impact factor: 10.154

6. Detailed analysis of neuromuscular transmission in a patient with the myasthenic syndrome sometimes associated with bronchogenic carcinoma.

Authors: D Elmqvist; E H Lambert
Journal: Mayo Clin Proc Date: 1968-10 Impact factor: 7.616

Eaton-Lambert syndrome: a clinical and electrophysiological study of a patient treated with 4-aminopyridine.

1. A study of some electrophysiological properties of human intercostal muscle.

2. Electromyography and electric stimulation of nerves in diseases of motor unit; observations on myasthenic syndrome associated with malignant tumors.

3. An electrophysiological and morphological study of the neuromuscular junction in patients with myasthenia gravis.

4. A neuromuscular transmission block produced by a cancer tissue extract derived from a patient with the myasthenic syndrome.

5. 4-aminopyridine--a new drug tested in the treatment of Eaton-Lambert syndrome.

6. Detailed analysis of neuromuscular transmission in a patient with the myasthenic syndrome sometimes associated with bronchogenic carcinoma.

7. Depression of bone marrow by guanidine.

8. Defects of neuromuscular transmission in syndromes other than myasthenia gravis.

9. Effects of 4-aminopyridine in Eaton Lambert Syndrome.

10. Effects of 4-aminopyridine in myasthenia gravis.

1. Improvement in neuromuscular transmission in myasthenia gravis by 3,4-diaminopyridine.

2. Electrophysiological study in neuromuscular junction disorders.