Literature DB >> 656256

Effects of 4-aminopyridine in Eaton Lambert Syndrome.

S Agoston, T van Weerden, P Westra, A Broekert.   

Abstract

The effects of 4-aminopyridine (a non-anticholinesterase antagonist of curare-like agents) on the evoked muscle action potentials (EMAP) in a patient with Eaton Lambert Syndrome are reported. On two separate occasions the i.v. administration of 0.31 mg kg(-1) and 0.62 mg kg(-1) was followed by a 300% increase of EMAP for about 2 h without serious side-effects.

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Year:  1978        PMID: 656256     DOI: 10.1093/bja/50.4.383

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN: 0007-0912            Impact factor:   9.166


  5 in total

1.  A review of 29 incidents involving 4-aminopyridine in non-target species reported to the ASPCA Animal Poison Control Center.

Authors:  Mary Kay McLean; Safdar Khan
Journal:  J Med Toxicol       Date:  2013-12

2.  Effect of 4-aminopyridine on muscle contractility in the cat [proceedings].

Authors:  W C Bowman; I W Rodger; A O Savage
Journal:  Br J Pharmacol       Date:  1979-07       Impact factor: 8.739

3.  Eaton-Lambert syndrome: a clinical and electrophysiological study of a patient treated with 4-aminopyridine.

Authors:  D B Sanders; Y I Kim; J F Howard; C A Goetsch
Journal:  J Neurol Neurosurg Psychiatry       Date:  1980-11       Impact factor: 10.154

4.  Aligned microchannel polymer-nanotube composites for peripheral nerve regeneration: Small molecule drug delivery.

Authors:  Ohan S Manoukian; Michael R Arul; Swetha Rudraiah; Ivo Kalajzic; Sangamesh G Kumbar
Journal:  J Control Release       Date:  2019-01-15       Impact factor: 9.776

Review 5.  Treatment for Lambert-Eaton myasthenic syndrome.

Authors:  Michael Keogh; Saam Sedehizadeh; Paul Maddison
Journal:  Cochrane Database Syst Rev       Date:  2011-02-16
  5 in total

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