Literature DB >> 6252780

The role of adjuvant therapy in Stage I ovarian cancer.

M M Hreshchyshyn, R C Park, J A Blessing, H J Norris, D Levy, L D Lagasse, W T Creasman.   

Abstract

Women with Stage I epithelial carcinoma of the ovary were initially treated by an extirpative operation and were subsequently randomized to either no further treatment, radiotherapy, or chemotherapy. Only two patients (6%) treated with chemotherapy developed recurrence, compared to five (17%) and seven (30%) patients in the no-treatment and radiotherapy regimens, respectively (P < 0.05). All patients, with the possible exception of those with Stage IA(1)g1, appeared to benefit from adjuvant chemotherapy compared to no treatment or radiotherapy.

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Year:  1980        PMID: 6252780     DOI: 10.1016/0002-9378(80)90024-1

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  8 in total

Review 1.  Pursuit of optimum outcomes in ovarian cancer: methodological approaches to therapy.

Authors:  D D Gibbs; M E Gore
Journal:  Drugs       Date:  2001       Impact factor: 9.546

Review 2.  Adjuvant (post-surgery) chemotherapy for early stage epithelial ovarian cancer.

Authors:  Brett A Winter-Roach; Henry C Kitchener; Theresa A Lawrie
Journal:  Cochrane Database Syst Rev       Date:  2012-03-14

Review 3.  Platinum-based adjuvant chemotherapy on moderate- and high-risk stage I and II epithelian ovarian cancer patients. Long-term single institution experience and literature review.

Authors:  José A García-Sáenz; Ana Custodio; Antonio Casado; José Antonio Vidart; Pluvio J Coronado; Miguel Martín; Sara López-Tarruella; Javier Puente; Cristina Fernández; Eduardo Díaz-Rubio
Journal:  Clin Transl Oncol       Date:  2011-02       Impact factor: 3.405

Review 4.  Progress in gynecologic cancer research: the Gynecologic Oncology Group experience.

Authors:  George A Omura
Journal:  Semin Oncol       Date:  2008-10       Impact factor: 4.929

5.  A study of the treatment of ovarian carcinoma.

Authors:  H Pickel
Journal:  Arch Gynecol       Date:  1983

Review 6.  Radiation Treatment in Women with Ovarian Cancer: Past, Present, and Future.

Authors:  Emma C Fields; William P McGuire; Lilie Lin; Sarah M Temkin
Journal:  Front Oncol       Date:  2017-08-21       Impact factor: 6.244

7.  Incidence and predictive factors for recurrent clear cell ovarian carcinoma: results from a single center in Thailand.

Authors:  Wikanda Hemman; Athithan Rattanaburi
Journal:  Obstet Gynecol Sci       Date:  2022-02-23

Review 8.  Adjuvant (post-surgery) chemotherapy for early stage epithelial ovarian cancer.

Authors:  Theresa A Lawrie; Brett A Winter-Roach; Pauline Heus; Henry C Kitchener
Journal:  Cochrane Database Syst Rev       Date:  2015-12-17
  8 in total

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