Literature DB >> 6251253

Molecular cloning of the Harvey sarcoma virus circular DNA intermediates. II. Further structural analyses.

H W Chang, C F Garon, E H Chang, D R Lowy, G L Hager, E M Scolnick, R Repaske, M A Martin.   

Abstract

Three species of unintegrated supercoiled Harvey sarcoma virus DNA (6.6, 6.0, and 5.4 kilobase pairs) have been molecularly cloned from Harvey sarcoma virus-infected cells. On the basis of restriction enzyme analyses, the 6.6- and 6.0-kilobase pair viral DNAs contain two and one copies, respectively, of a 650-base pair DNA segment which contains sequences present at the 3' and 5' termini of the viral genome. R-loop structures formed between Moloney leukemia virus RNA and the cloned Harvey sarcoma virus DNA indicated that about 500 base pairs of the 650-base pair repeating segment was complementary to the 3' end of the viral RNA. During amplification in the Escherichia coli host, some recombinants containing the 6.6- or the 6.0-kilobase pair Harvey sarcoma virus DNA insert acquired or lost the complete 650-base pair DNA segment. These changes occurred in both recA+ and recA- E. coli.

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Year:  1980        PMID： 6251253      PMCID： PMC288610     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  17 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

2.  Different mechanisms for morphologic reversion of a clonal population of murine sarcoma virus-transformed nonproducer cells.

Authors:  W I Bensinger; K C Robbins; J S Greenberger; S A Aaronson
Journal:  Virology       Date:  1977-04       Impact factor: 3.616

3.  Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors:  P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal:  J Mol Biol       Date:  1977-06-15       Impact factor: 5.469

4.  Comparison of the genomic organization of Kirsten and Harvey sarcoma viruses.

Authors:  T Y Shih; D R Williams; M O Weeks; J M Maryak; W C Vass; E M Scolnick
Journal:  J Virol       Date:  1978-07       Impact factor: 5.103

5.  Deletions within E. coli plasmids carrying yeast rDNA.

Authors:  A Cohen; D Ram
Journal:  Gene       Date:  1978-04       Impact factor: 3.688

6.  EK2 derivatives of bacteriophage lambda useful in the cloning of DNA from higher organisms: the lambdagtWES system.

Authors:  P Leder; D Tiemeier; L Enquist
Journal:  Science       Date:  1977-04-08       Impact factor: 47.728

7.  Lac repressor binding to non-operator DNA: detailed studies and a comparison of eequilibrium and rate competition methods.

Authors:  S Y Lin; A D Riggs
Journal:  J Mol Biol       Date:  1972-12-30       Impact factor: 5.469

8.  The integrated genome of murine leukemia virus.

Authors:  D Steffen; R A Weinberg
Journal:  Cell       Date:  1978-11       Impact factor: 41.582

9.  Elimination of the sarcoma genome from murine sarcoma virus transformed cat cells.

Authors:  A S Frankel; D K Haapala; R L Neubauer; P J Fischinger
Journal:  Science       Date:  1976-03-26       Impact factor: 47.728

10.  Structure of the genome of Moloney murine leukemia virus: a terminally redundant sequence.

Authors:  J M Coffin; T C Hageman; A M Maxam; W A Haseltine
Journal:  Cell       Date:  1978-04       Impact factor: 41.582
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  14 in total

1.  An altered DNA sequence encompassing the ras gene of Harvey murine sarcoma virus.

Authors:  S Yasuda; M Furuichi; E Soeda
Journal:  Nucleic Acids Res       Date:  1984-07-25       Impact factor: 16.971

2.  Molecular cloning of avian sarcoma virus closed circular DNA: structural and biological characterization of three recombinant clones.

Authors:  P E Highfield; L F Rafield; T M Gilmer; J T Parsons
Journal:  J Virol       Date:  1980-10       Impact factor: 5.103

3.  Nucleotide sequences of integrated Moloney sarcoma provirus long terminal repeats and their host and viral junctions.

Authors:  R Dhar; W L McClements; L W Enquist; G F Vande Woude
Journal:  Proc Natl Acad Sci U S A       Date:  1980-07       Impact factor: 11.205

4.  Virus-induced gene mutations of eukaryotic cells.

Authors:  E Geissler; M Theile
Journal:  Hum Genet       Date:  1983       Impact factor: 4.132

5.  Generation of novel, biologically active Harvey sarcoma viruses via apparent illegitimate recombination.

Authors:  M P Goldfarb; R A Weinberg
Journal:  J Virol       Date:  1981-04       Impact factor: 5.103

6.  Cloning of endogenous murine leukemia virus-related sequences from chromosomal DNA of BALB/c and AKR/J mice: identification of an env progenitor of AKR-247 mink cell focus-forming proviral DNA.

Authors:  A S Khan; W P Rowe; M A Martin
Journal:  J Virol       Date:  1982-11       Impact factor: 5.103

7.  Mapping of transforming region of the Harvey murine sarcoma virus genome by using insertion-deletion mutants constructed in vitro.

Authors:  C M Wei; D R Lowy; E M Scolnick
Journal:  Proc Natl Acad Sci U S A       Date:  1980-08       Impact factor: 11.205

8.  Dual evolutionary origin for the rat genetic sequences of Harvey murine sarcoma virus.

Authors:  R W Ellis; D DeFeo; J M Maryak; H A Young; T Y Shih; E H Chang; D R Lowy; E M Scolnick
Journal:  J Virol       Date:  1980-11       Impact factor: 5.103

9.  Functional organization of the Harvey murine sarcoma virus genome.

Authors:  E H Chang; J M Maryak; C M Wei; T Y Shih; R Shober; H L Cheung; R W Ellis; G L Hager; E M Scolnick; D R Lowy
Journal:  J Virol       Date:  1980-07       Impact factor: 5.103

10.  Molecular cloning of murine endogenous viral sequences and expression of a newly constructed recombinant murine leukemia virus DNA in transfected mink cells.

Authors:  F A van der Hoorn; C Onnekink; H van der Putten; M Zijlstra; H P Bloemers
Journal:  Proc Natl Acad Sci U S A       Date:  1982-03       Impact factor: 11.205
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