Literature DB >> 1257745

Elimination of the sarcoma genome from murine sarcoma virus transformed cat cells.

A S Frankel, D K Haapala, R L Neubauer, P J Fischinger.   

Abstract

Cat cells transformed by Moloney murine sarcoma virus contain virus-specific sequences in their RNA and DNA. Cloned, spontaneous revertant cell lines derived from clones of these cells had no evidence of the sarcoma genome in the cell RNA or DNA as judged by RNA-complementary DNA or DNA-complementary DNA hybridizations. ?This is apparently the first report of loss of a transforming genome in a revertant cell line.

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Year:  1976        PMID： 1257745     DOI： 10.1126/science.1257745

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  12 in total

1.  Quantitation and localization of Rous sarcoma virus-specific RNA in transformed and revertant field vole cells.

Authors:  R A Krzyzek; A F Lau; P K Vogt; A J Faras
Journal:  J Virol       Date:  1978-02       Impact factor: 5.103

2.  Glucocorticoids induce focus formation and increase sarcoma viral expression in a mink cell line that contains a murine sarcoma viral genome.

Authors:  D R Lowy; E M Scolnick
Journal:  J Virol       Date:  1978-01       Impact factor: 5.103

3.  Foreign DNA sequences in crown gall teratomas and their fate during the loss of the tumorous traits.

Authors:  F Yang; A L Montoya; D J Merlo; M H Drummond; M D Chilton; E W Nester; M P Gordon
Journal:  Mol Gen Genet       Date:  1980

4.  Persistent expression of v-mos oncogene in transformed cells that revert to nonmalignancy after prolonged treatment with interferon.

Authors:  D Sergiescu; J Gerfaux; A M Joret; C Chany
Journal:  Proc Natl Acad Sci U S A       Date:  1986-08       Impact factor: 11.205

5.  Revertant seedlings from crown gall tumors retain a portion of the bacterial Ti plasmid DNA sequences.

Authors:  F Yang; R B Simpson
Journal:  Proc Natl Acad Sci U S A       Date:  1981-07       Impact factor: 11.205

6.  Molecular cloning of the Harvey sarcoma virus circular DNA intermediates. II. Further structural analyses.

Authors:  H W Chang; C F Garon; E H Chang; D R Lowy; G L Hager; E M Scolnick; R Repaske; M A Martin
Journal:  J Virol       Date:  1980-02       Impact factor: 5.103

7.  Effect of helper virus on the number of murine sarcoma virus DNA copies in infected mammalian cells.

Authors:  A E Frankel; J H Gilbert; P J Fischinger
Journal:  J Virol       Date:  1977-09       Impact factor: 5.103

Review 8.  Hematopoietic growth and differentiation factors and the reversibility of malignancy: cell differentiation and by-passing of genetic defects in leukemia.

Authors:  L Sachs
Journal:  Med Oncol Tumor Pharmacother       Date:  1986

9.  Flat revertants isolated from Kirsten sarcoma virus-transformed cells are resistant to the action of specific oncogenes.

Authors:  M Noda; Z Selinger; E M Scolnick; R H Bassin
Journal:  Proc Natl Acad Sci U S A       Date:  1983-09       Impact factor: 11.205

10.  Rate of divergence of cellular sequences homologous to segments of Moloney sarcoma virus.

Authors:  A E Frankel; P J Fischinger
Journal:  J Virol       Date:  1977-01       Impact factor: 5.103
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