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Literature DB >> 6241227

Repeated treatment with antidepressant drugs increases the behavioural response to apomorphine.

Abstract

The effect of repeated treatment (twice a day for 14 days) with antidepressant drugs (AD): imipramine, amitriptyline, zimelidine, citalopram and mianserin on the behavioural response to apomorphine in rats (open field test) was investigated. AD studied, given alone in a single dose or repeatedly, do not change the rats behaviour. A repeated but not single-dose treatment with AD facilitates the behaviour stimulation induced by apomorphine. This facilitation is observed 2 hours after the last dose of imipramine, zimelidine, citalopram and mianserin but 72 hours after the last dose of amitriptyline. The results presented suggest that the AD given repeatedly are able to increase the responsiveness of the brain DA system, probably the mesolimbic one.

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Year: 1984 PMID： 6241227 DOI： 10.1007/bf01249099

Source DB: PubMed Journal: J Neural Transm Impact factor: 3.575

32 in total

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Authors: J Maj; E Mogilnicka; V Klimek
Journal: J Pharm Pharmacol Date: 1977-09 Impact factor: 3.765

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Journal: Neurosci Lett Date: 1979-08 Impact factor: 3.046

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Authors: E Przegaliński; L Baran; J Siwanowicz; K Bigajska
Journal: Pharmacol Biochem Behav Date: 1984-11 Impact factor: 3.533

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Authors: A R Green; J F Deakin
Journal: Nature Date: 1980-05-22 Impact factor: 49.962

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Authors: S H Snyder; S J Peroutka
Journal: Pharmacopsychiatria Date: 1982-07

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Authors: L A Chiodo; S M Antelman
Journal: Nature Date: 1980-10-02 Impact factor: 49.962

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Authors: J Maj; Z Rogóz; G Skuza
Journal: J Pharm Pharmacol Date: 1983-03 Impact factor: 3.765

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Authors: J Maj; Z Rogóz; G Skuza; H Sowińska
Journal: J Neural Transm Date: 1982 Impact factor: 3.575

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Authors: B H Westerink; B Lejeune; J Korf; H M Van Praag
Journal: Eur J Pharmacol Date: 1977-03-21 Impact factor: 4.432

10. Differential effect of chronic desipramine and amitriptyline treatment on rat brain adrenergic and serotonergic receptors.

Authors: S W Tang; P Seeman; S Kwan
Journal: Psychiatry Res Date: 1981-04 Impact factor: 3.222

20 in total

1. Reversal of stress-induced anhedonia by the atypical antidepressants, fluoxetine and maprotiline.

Authors: R Muscat; M Papp; P Willner
Journal: Psychopharmacology (Berl) Date: 1992 Impact factor: 4.530

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Authors: J Maj; Z Rogóz; G Skuza; H Sowińska
Journal: J Neural Transm Gen Sect Date: 1989

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Authors: G B Baker; A J Greenshaw
Journal: Cell Mol Neurobiol Date: 1989-03 Impact factor: 5.046

4. Effects of citalopram on dopamine D2 receptor expression in the rat brain striatum.

Authors: K Kameda; I Kusumi; K Suzuki; J Miura; Y Sasaki; T Koyama
Journal: J Mol Neurosci Date: 2000 Feb-Apr Impact factor: 3.444

5. Chronic effects of clomipramine and clorgyline on regional levels of brain amines and acid metabolites in rats.

Authors: D D Mousseau; A J Greenshaw
Journal: J Neural Transm Date: 1989 Impact factor: 3.575

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Authors: A Delini-Stula; E Mogilnicka
Journal: J Neural Transm Date: 1988 Impact factor: 3.575

10. Effect of prenatal exposure to tianeptine on different neurotransmitter receptors and 5-HT-stimulated inositol phosphate formation in rat brain.

Authors: G Romero; E Toscano; D Montero; M C De Felipe; J Del Rio
Journal: J Neural Transm Gen Sect Date: 1992