Literature DB >> 6238931

In-vitro activity of enoxacin, ofloxacin, norfloxacin and nalidixic acid.

A Bauernfeind, U Ullmann.   

Abstract

The in-vitro activity of enoxacin, ofloxacin, norfloxacin and nalidixic acid was determined against 1499 Gram-negative and 279 Gram-positive isolates from different clinical institutions in the Federal Republic of Germany. 90% of all Enterobacteriaceae were inhibited by 0.5 mg/l. Glucose non-fermenting Gram-negative rods and staphylococci were less sensitive to all 4-quinolones. All Gram-negative strains selected for resistance to nalidixic acid were significantly less sensitive to the new generation of 4-quinolones tested.

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Year:  1984        PMID: 6238931     DOI: 10.1093/jac/14.suppl_c.33

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN: 0305-7453            Impact factor:   5.790


  21 in total

1.  [In vitro activity of new quinolones against nonfermenters and references to sensitivity tests].

Authors:  H Grimm
Journal:  Infection       Date:  1986       Impact factor: 3.553

2.  [Dependence of the bactericidal activity and mutant selection of 4-quinolones on their serum concentration levels].

Authors:  A Bauernfeind; C Petermüller; B Heinrich; R Gablac
Journal:  Infection       Date:  1986       Impact factor: 3.553

3.  Effect of enoxacin on colonic microflora of healthy volunteers.

Authors:  C Edlund; A Lidbeck; L Kager; C E Nord
Journal:  Eur J Clin Microbiol       Date:  1987-06       Impact factor: 3.267

4.  Further methodological improvement in antibiotic bone concentration measurements: penetration of ofloxacin into bone and cartilage.

Authors:  D H Wittmann; E Kotthaus
Journal:  Infection       Date:  1986       Impact factor: 3.553

5.  Study of the cerebrospinal fluid penetrability of ofloxacin.

Authors:  G Stübner; W Weinrich; U Brands
Journal:  Infection       Date:  1986       Impact factor: 3.553

6.  Determination of norfloxacin and ciprofloxacin concentrations in serum and urine by high-pressure liquid chromatography.

Authors:  S J Morton; V H Shull; J D Dick
Journal:  Antimicrob Agents Chemother       Date:  1986-08       Impact factor: 5.191

Review 7.  [Enoxacin: spectrum and activity of its antibacterial effect].

Authors:  A Bauernfeind; H Flamm; H Grimm; H Hahn; F Kayser; W Opferkuch; J Potel; R Malottke; H G Sonntag; W H Traub
Journal:  Infection       Date:  1986       Impact factor: 3.553

8.  The place of quinolones in antibacterial therapy in hospitals.

Authors:  R P Mouton
Journal:  Pharm Weekbl Sci       Date:  1986-02-21

9.  Penetration of enoxacin into bronchial secretions.

Authors:  I W Fong; A Vandenbroucke; M Simbul
Journal:  Antimicrob Agents Chemother       Date:  1987-05       Impact factor: 5.191

Review 10.  Norfloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Authors:  B Holmes; R N Brogden; D M Richards
Journal:  Drugs       Date:  1985-12       Impact factor: 9.546

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