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Literature DB >> 6231245

Functional characterization of the H-2Dp gene product.

E McLaughlin-Taylor, J G Woodward, M J Macchi, M McMillan, J A Frelinger.

Abstract

A lambda clone containing the Dp gene was used to transform L cells. The Dp product expressed was identified by two-dimensional gel electrophoresis and flow cytometry. The Dp product expressed by the L cells was recognized by Dp-specific but not Kp-specific killer T cells. This killing was inhibited by monoclonal antibodies specific for Dp but not Kp or Kk antigens. Similarly, lymphocytic choriomeningitis virus (LCMV) killer T cells from B10.P mice were able to kill LCMV-infected L12a cells, but not LCMV-infected Ltk+. Again only Dp monoclonal antibodies could inhibit this killing.

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Year: 1984 PMID： 6231245 DOI： 10.1007/bf00364764

Source DB: PubMed Journal: Immunogenetics ISSN： 0093-7711 Impact factor: 2.846

29 in total

1. Use of cloned H-2 genes for study of H-2-restricted cytotoxicity: Ld is the LCMV restriction element for H-2d.

Authors: J A Frelinger; A Orn; P R Brayton; L Hood
Journal: Transplant Proc Date: 1983-12 Impact factor: 1.066

2. Specific recognition of the product of a transferred major histocompatibility complex gene by cytotoxic T lymphocytes.

Authors: J G Woodward; A Orn; R C Harmon; R S Goodenow; L Hood; J A Frelinger
Journal: Proc Natl Acad Sci U S A Date: 1982-06 Impact factor: 11.205

3. DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.

Authors: M Wigler; A Pellicer; S Silverstein; R Axel; G Urlaub; L Chasin
Journal: Proc Natl Acad Sci U S A Date: 1979-03 Impact factor: 11.205

4. An improved method for isolation of H-2 and Ia alloantigens with immunoprecipitation induced by protein A-bearing staphylococci.

Authors: S E Cullen; B D Schwartz
Journal: J Immunol Date: 1976-07 Impact factor: 5.422

5. H-2 antigens as genetic markers: a two-dimensional gel electrophoretic study.

Authors: J A Sawicki; C J Epstein
Journal: Immunogenetics Date: 1981 Impact factor: 2.846

6. Genetic polymorphism of beta 2-microglobulin (B2m) maps to the H-3 region of chromosome 2.

Authors: J Michaelson
Journal: Immunogenetics Date: 1981 Impact factor: 2.846

7. Identification of the class I genes of the mouse major histocompatibility complex by DNA-mediated gene transfer.

Authors: R S Goodenow; M McMillan; M Nicolson; B T Sher; K Eakle; N Davidson; L Hood
Journal: Nature Date: 1982-11-18 Impact factor: 49.962

8. Genetic mapping in the major histocompatibility complex by restriction enzyme site polymorphisms: most mouse class I genes map to the Tla complex.

Authors: A Winoto; M Steinmetz; L Hood
Journal: Proc Natl Acad Sci U S A Date: 1983-06 Impact factor: 11.205

9. Hybridoma cell lines secreting monoclonal antibodies to mouse H-2 and Ia antigens.

Authors: K Ozato; N Mayer; D H Sachs
Journal: J Immunol Date: 1980-02 Impact factor: 5.422

10. Ir-genes in H-2 regulate generation of anti-viral cytotoxic T cells. Mapping to K or D and dominance of unresponsiveness.

Authors: R M Zinkernagel; A Althage; S Cooper; G Kreeb; P A Klein; B Sefton; L Flaherty; J Stimpfling; D Shreffler; J Klein
Journal: J Exp Med Date: 1978-08-01 Impact factor: 14.307

4 in total

4. New family of exon-shuffled recombinant genes reveals extensive interdomain interactions in class I histocompatibility antigens and identifies residues involved.

Authors: M J Darsley; H Takahashi; M J Macchi; J A Frelinger; K Ozato; E Appella
Journal: J Exp Med Date: 1987-01-01 Impact factor: 14.307